Kristel Eggermont

Allen Institute for Brain Science — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index6.8kcitations63works9.32yr avg
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Research Topics

Pluripotent Stem Cells Research(12), Plant-Microbe Interactions and Immunity(9), Virus-based gene therapy research(8), RNA Interference and Gene Delivery(8), CRISPR and Genetic Engineering(8)

Publications63 total

<i>C21ORF2</i> mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis
Brain·2024· 9 citedOpen Access
P06-15 Temporal transcriptomic analysis reveals Parkinson's diseaserelated perturbations upon increasing polychlorinated biphenyl levels in human iPSC-derived dopaminergic neurons
Toxicology Letters·2024
<i>PMP22</i> duplication dysregulates lipid homeostasis and plasma membrane organization in developing human Schwann cells
Brain·2024· 18 citedOpen Access
Molecular insights into PCB neurotoxicity: Comparing transcriptomic responses across dopaminergic neurons, population blood cells, and Parkinson's disease pathology
Environment International·2024· 10 citedOpen Access
Defective Schwann cell lipid metabolism alters plasma membrane dynamics in Charcot-Marie-Tooth disease 1A
2023· 4 citedOpen Access
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
Brain·2022· 124 citedOpen Access
Transcriptomics analysis of human iPSC-derived dopaminergic neurons reveals a novel model for sporadic Parkinson’s disease
Molecular Psychiatry·2022· 15 cited
<i>C21orf2</i> mutations found in ALS disrupt primary cilia function
2022· 5 citedOpen Access
Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction
Brain·2021· 49 citedOpen Access
HDAC6 inhibition restores TDP‐43 pathology and axonal transport defects in human motor neurons with <i>TARDBP</i> mutations
The EMBO Journal·2021· 99 citedOpen Access
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells
Nature Protocols·2020· 43 citedOpen Access
In vitro modeling of dysfunctional glial cells in neurodegenerative diseases using human pluripotent stem cells
2019
Generation of a human induced pluripotent stem cell–based model for tauopathies combining three microtubule‐associated protein TAU mutations which displays several phenotypes linked to neurodegeneration
Alzheimer s & Dementia·2018· 51 citedOpen Access
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Stem Cell Reports·2018· 5 citedOpen Access
SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells
Stem Cell Reports·2018· 118 citedOpen Access
Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals
Antiviral Research·2017· 56 citedOpen Access
[P3–080]: AN ACADEMIC‐PRIVATE PARTNERSHIP FOR THE VALIDATION OF NEW MODELS TO UNDERSTAND TAU‐RELATED HYPEREXCITABILITY AND AGGREGATION USING HUMAN‐INDUCED PLURIPOTENT STEM CELLS
Alzheimer s & Dementia·2017
H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro
Stem Cell Reports·2016· 21 citedOpen Access
Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Stem Cell Reports·2015· 148 citedOpen Access
Hematopoietic Stem/Progenitor Cells Directly Contribute to Arteriosclerotic Progression via Integrin β2
Stem Cells·2014· 15 citedOpen Access
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Frequent Co-authors

Catherine M. Verfaillie(19), Willem F. Broekaert(13), Bart P. H. J. Thomma(9), Iris A. M. A. Penninckx(8), Ludo Van Den Bosch(8), Philip Van Damme(6), Bruno P.A. Cammue(5), Franky R. G. Terras(5), Inge J.W.M. Goderis(5), Veerle Baekelandt(5), Zeger Debyser(5), Ruben Boon(5), Esther Wolfs(5), Rupert W. Osborn(4), Laura Ordovás(4), Veerle Vanslembrouck(4), Ivo Lambrichts(4), Martine Geraerts(4), Bart Nuttin(3), Mariaelena Pistoni(3)