José A. Cisneros

Austrian Academy of Sciences — Austria

Immunology and Microbiology · Life Sciences

21h-index1.2kcitations31works27.02yr avg
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Research Topics

HIV Research and Treatment(8), HIV/AIDS drug development and treatment(8), Macrophage Migration Inhibitory Factor(7), Cannabis and Cannabinoid Research(6), Synthesis of heterocyclic compounds(4)

Publications31 total

Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation
Nature Communications·2024· 27 citedOpen Access
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling
ACS Chemical Biology·2023· 29 citedOpen Access
Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead
ACS Medicinal Chemistry Letters·2021· 24 citedOpen Access
Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV
Antiviral Research·2019· 27 citedOpen Access
Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection
Proceedings of the National Academy of Sciences·2018Open Access
Front Cover: Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor (ChemMedChem 11/2018)
ChemMedChem·2018Open Access
Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor
ChemMedChem·2018· 18 cited
From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection
Proceedings of the National Academy of Sciences·2017· 36 citedOpen Access
Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor
ACS Medicinal Chemistry Letters·2017· 11 citedOpen Access
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography
Proceedings of the National Academy of Sciences·2017· 49 citedOpen Access
JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules
ACS Medicinal Chemistry Letters·2017· 29 citedOpen Access
CCDC 1514977: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Systematic Study of Effects of Structural Modifications on the Aqueous Solubility of Drug-like Molecules
ACS Medicinal Chemistry Letters·2016· 40 citedOpen Access
A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors
Journal of the American Chemical Society·2016· 46 cited
Irregularities in enzyme assays: The case of macrophage migration inhibitory factor
Bioorganic & Medicinal Chemistry Letters·2016· 24 citedOpen Access
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium
Bioorganic & Medicinal Chemistry Letters·2015· 14 citedOpen Access
Design, Synthesis, and Protein Crystallography of Biaryltriazoles as Potent Tautomerase Inhibitors of Macrophage Migration Inhibitory Factor
Journal of the American Chemical Society·2015· 76 citedOpen Access
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase–dihydrofolate reductase
Bioorganic & Medicinal Chemistry Letters·2014· 36 citedOpen Access
Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility
Bioorganic & Medicinal Chemistry Letters·2013· 39 citedOpen Access
Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility
Bioorganic & Medicinal Chemistry Letters·2013· 35 citedOpen Access
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Frequent Co-authors

William L. Jorgensen(19), Karen S. Anderson(10), Michael J. Robertson(8), Krasimir A. Spasov(6), Silvia Ortega‐Gutiérrez(5), María L. López-Rodrı́guez(4), Shalley N. Kudalkar(4), V.L. Newhouse(3), Kathleen M. Frey(3), Mariela Bollini(3), Won‐Gil Lee(3), Margarita Valhondo(3), Jagadish Beloor(3), Elias Quijano(3), W. Mark Saltzman(3), Priti Kumar(3), S.G. Krimmer(3), D. Censor(2), Giulio G. Muccioli(2), Cong Xu(2)