Mrinal K. Sarkar

Immunology and Microbiology · Life Sciences

35h-index4.0kcitations114works3.92yr avg
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Research Topics

Psoriasis: Treatment and Pathogenesis(40), Dermatology and Skin Diseases(30), Cytokine Signaling Pathways and Interactions(18), Systemic Lupus Erythematosus Research(13), interferon and immune responses(11)

Publications114 total

Spatial transcriptomics identifies differentiation, lipid metabolism, and retinoid pathway alterations in acne vulgaris
JCI Insight·2026Open Access
Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis
Nature Communications·2025Open Access
RUNX1 is expressed in a subpopulation of dermal fibroblasts and is associated with disease severity of systemic sclerosis
Annals of the Rheumatic Diseases·2025Open Access
239 A Transcriptomic Atlas of Healthy Human Skin Links Regional Identity to Inflammatory Disease
Journal of Investigative Dermatology·2025
Endothelin-2 from Keratinocytes and its Association with Itch in Skin Diseases
Journal of Investigative Dermatology·2025· 1 citedOpen Access
The endoplasmic reticulum autophagy receptor TEX264 drives epidermal differentiation and is dysregulated in Darier disease
2025Open Access
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes
Nature Communications·2025· 5 citedOpen Access
Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier
Nature Communications·2025· 2 citedOpen Access
0513 Flower directs apically polarized trafficking of lamellar bodies to establish the epidermal barrier
Journal of Investigative Dermatology·2025
0548 Hailey-Hailey disease models reveal impaired cadherin expression and localization along with actin dysregulation as key pathogenic drivers that weaken intercellular adhesion
Journal of Investigative Dermatology·2025Open Access
0501 Keratin 5 knockout dysregulates keratinocyte differentiation and epidermal morphogenesis and reveals potential pathogenic drivers of epidermolysis bullosa simplex
Journal of Investigative Dermatology·2025
0583 Generation of novel immortalized keratinocyte lines through overexpression of human telomerase and CRISPR-Cas9 KO of CDKN2A
Journal of Investigative Dermatology·2025Open Access
Targeting the IL-36 receptor with spesolimab mitigates residual inflammation and prevents generalized pustular psoriasis flares
Journal of Clinical Investigation·2025· 1 citedOpen Access
VGLL3-centered network connects placental, vascular, and immune defects in preeclampsia
2025· 1 citedOpen Access
A Transcriptomic Atlas of Healthy Human Skin Links Regional Identity to Inflammatory Disease
2025· 3 citedOpen Access
Integration of GWAS, QTLs and keratinocyte functional assays reveals molecular mechanisms of atopic dermatitis
Nature Communications·2025· 8 citedOpen Access
Characterizing the immune infiltrate in secondary syphilis: implications for transmission and pathology
Frontiers in Immunology·2025· 1 citedOpen Access
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
Nature Communications·2025· 38 citedOpen Access
IL-1 signaling enrichment in inflammatory skin disease loci with higher risk allele frequencies in African ancestry
2025Open Access
Keratin 16 spatially inhibits type I interferon responses in stressed and diseased skin
2024· 2 citedOpen Access
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Frequent Co-authors

Jóhann E. Guðjónsson(44), Lam C. Tsoi(27), Xianying Xing(27), William R. Swindell(21), J. Michelle Kahlenberg(21), John J. Voorhees(19), Ranjitha Uppala(17), Allison C. Billi(15), James T. Elder(13), Paul W. Harms(12), Yun Liang(11), Nicole L. Ward(11), Shuai Shao(10), Matthew T. Patrick(9), Emanual Maverakis(9), Bethany E. Perez White(8), Olesya Plazyo(8), Rachael Wasikowski(8), Chang Zeng(8), Philip E. Stuart(7)