William R. Swindell

The University of Texas Southwestern Medical Center — United States

Immunology and Microbiology · Life Sciences

49h-index8.9kcitations141works2.52yr avg
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Research Topics

Psoriasis: Treatment and Pathogenesis(27), Dermatology and Skin Diseases(26), Genetics, Aging, and Longevity in Model Organisms(21), Adipose Tissue and Metabolism(16), Cytokine Signaling Pathways and Interactions(14)

Publications141 total

Adipocyte-Specific Deletion of Sine Oculis Homeobox Homolog 1 Inhibits Lipolysis and Reduces Skin Fibrosis
JCI Insight·2026Open Access
Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database
npj Aging·2025Open Access
Evaluating the Current Opioid Misuse Measure (COMM) as a Tool to Inform Management of Vaso-occlusive Episodes Among Hospitalized Sickle Cell Disease Patients
Clinical Journal of Pain·2025
Meta-Analysis of Gene Expression in Bulk-Processed Post-Mortem Spinal Cord from ALS Patients and Normal Controls
NeuroSci·2025Open Access
Reporting quality, effect sizes, and biases for aging interventions: a methodological appraisal of the DrugAge database
2025Open Access
VGLL3-centered network connects placental, vascular, and immune defects in preeclampsia
2025· 1 citedOpen Access
A Novel Butyrate Derivative, Zinc Dibutyroyllysinate, Blunts Microphthalmia-Associated Transcription Factor Expression and Up-Regulates Retinol and Differentiation Pathway mRNAs in a Full-Thickness Human Skin Model
International Journal of Molecular Sciences·2025Open Access
Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis
2024Open Access
Meta-analysis of differential gene expression in lower motor neurons isolated by laser capture microdissection from post-mortem ALS spinal cords
Frontiers in Genetics·2024· 3 citedOpen Access
A critical role for IFN-β signaling for IFN-κ induction in keratinocytes
Frontiers in Lupus·2024· 11 citedOpen Access
Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling
JCI Insight·2024· 10 citedOpen Access
HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling
iScience·2024· 8 citedOpen Access
Sine Oculis Homeobox Homolog 1 Modulates Early Features of Systemic Sclerosis Skin Fibrosis
SSRN Electronic Journal·2024Open Access
Formylpeptide receptor 1 contributes to epidermal barrier dysfunction-induced skin inflammation through NOD-like receptor C4-dependent keratinocyte activation
British Journal of Dermatology·2023· 5 cited
Acetyl Zingerone: A Photostable Multifunctional Skincare Ingredient That Combats Features of Intrinsic and Extrinsic Skin Aging
Antioxidants·2023· 14 citedOpen Access
Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin
Cell Reports·2023· 50 citedOpen Access
Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs
JID Innovations·2022· 6 citedOpen Access
Isosorbide Fatty Acid Diesters Have Synergistic Anti-Inflammatory Effects in Cytokine-Induced Tissue Culture Models of Atopic Dermatitis
International Journal of Molecular Sciences·2022· 9 citedOpen Access
Metformin has heterogeneous effects on model organism lifespans and is beneficial when started at an early age in <i>Caenorhabditis elegans</i>: A systematic review and meta‐analysis
Aging Cell·2022· 22 citedOpen Access
Transcriptomic Analysis of Fumarate Compounds Identifies Unique Effects of Isosorbide Di-(Methyl Fumarate) on NRF2, NF-kappaB and IRF1 Pathway Genes
Pharmaceuticals·2022· 8 citedOpen Access
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Frequent Co-authors

Jóhann E. Guðjónsson(29), Xianying Xing(21), Mrinal K. Sarkar(15), John J. Voorhees(15), Lam C. Tsoi(13), James T. Elder(13), Andrew Johnston(13), Paul W. Harms(10), Rajan P. Nair(9), Yun Liang(8), J. Michelle Kahlenberg(8), Nicole L. Ward(7), Ranjitha Uppala(5), Philip E. Stuart(5), Emanual Maverakis(4), Maria A. Beamer(4), Allison C. Billi(4), Shuai Shao(3), Matthew T. Patrick(3), Spiro Getsios(3)