Michael M. Hoffman

University Health Network — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index15.8kcitations165works136.92yr avg
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Research Topics

Genomics and Chromatin Dynamics(40), Cancer Genomics and Diagnostics(36), Epigenetics and DNA Methylation(28), Genomics and Phylogenetic Studies(26), Head and Neck Cancer Studies(22)

Publications162 total

Simulating cell-free chromatin using preclinical cancer models for liquid biopsy applications
iScience·2025Open Access
Non-invasive detection and classification of lymphoma via cell-free DNA methylation profiling
Blood·2025Open Access
TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods: a Korean translation
The Ewha Medical Journal·2025· 3 citedOpen Access
Abstract 4663: Human papillomavirus circulating tumor DNA for risk stratification in cervical cancer
Cancer Research·2025
LINE1 and PRC2 control nucleolar organization and repression of the 8C state in human ESCs
Developmental Cell·2024· 20 cited
LINE1 promotes nuclear compartmentalization to repress the 8-cell state in embryonic stem cells
2024· 1 citedOpen Access
A renewed call for open artificial intelligence in biomedicine
2024Open Access
Epigenomic Prognosis: Predicting fetal growth restriction beyond ultrasound markers
Placenta·2024Open Access
Annotation of nuclear lncRNAs based on chromatin interactions
PLoS ONE·2024· 2 citedOpen Access
TRIPOD+AI statement: updated guidance for reporting clinical prediction models that use regression or machine learning methods
BMJ·2024· 1.4k citedOpen Access
SWATH-MS as a strategy for CHO host cell protein identification and quantification supporting the characterization of mAb purification platforms
Journal of Biotechnology·2024· 5 cited
Metrics reloaded: recommendations for image analysis validation
Nature Methods·2024· 335 citedOpen Access
Understanding metric-related pitfalls in image analysis validation
Nature Methods·2024· 152 citedOpen Access
Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
Genome biology·2024· 25 citedOpen Access
Simulating cell-free chromatin using preclinical models for cancer-specific biomarker discovery
2023· 2 citedOpen Access
Identification of Mispairing Omic Signatures in Chinese Hamster Ovary (CHO) Cells Producing a Tri-Specific Antibody
Biomedicines·2023· 7 citedOpen Access
Segzoo: a turnkey system that summarizes genome annotations
2023Open Access
Segzoo: a turnkey system that summarizes genome annotations: results
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Segzoo
2023Open Access
Segzoo: a turnkey system that summarizes genome annotations: data
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
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Frequent Co-authors

William Stafford Noble(10), Anshul Kundaje(9), Mehran Karimzadeh(7), Maxwell W. Libbrecht(6), Ben Van Calster(5), Ben Glocker(5), Lena Maier‐Hein(5), Jeffrey A. Bilmes(5), Ewan Birney(4), Manolis Kellis(4), Zhiping Weng(4), Casey S. Greene(4), Gary S. Collins(4), Shu Yi Shen(4), Scott V. Bratman(4), Daniel D. De Carvalho(4), Orion J. Buske(4), Annika Reinke(4), Patrick Godau(4), Minu D. Tizabi(4)