Susan M. Kingsman

Oxford BioMedica (United Kingdom) — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

60h-index11.8kcitations182works0.02yr avg
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Research Topics

Virus-based gene therapy research(51), Fungal and yeast genetics research(43), HIV Research and Treatment(36), RNA and protein synthesis mechanisms(26), CRISPR and Genetic Engineering(25)

Publications182 total

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial
The Lancet·2014· 433 cited
Tolérance et efficacité de la thérapie génique lentivirale de la dopamine Prosavin® dans la maladie de Parkinson : résultats préliminaires d’un essai clinique de phase I
Neurochirurgie·2010
P2.205 A phase I/II clinical trial to evaluate the safety and efflcacy of ProSavin®, a gene therapy approach for Parkinson's disease
Parkinsonism & Related Disorders·2009
Dopamine Gene Therapy for Parkinson’s Disease in a Nonhuman Primate Without Associated Dyskinesia
Science Translational Medicine·2009· 177 cited
Development of lentiviral vectors for haemophilia a gene therapy
VUBIR (Vrije Universiteit Brussel)·2008
Identification and functional validation of MHC class I epitopes in the tumor-associated antigen 5T4
International Immunology·2008· 25 citedOpen Access
Determination of the profile and site preference of lentiviral vector integration in primary astrocyte cultures
Blood Cells Molecules and Diseases·2008
Analysis of factor VIII mediated suppression of lentiviral vector titres
Gene Therapy·2007· 34 cited
Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses
Cancer Immunology Immunotherapy·2007· 85 citedOpen Access
Evaluation of codon-optimized factor VIII genes in the development of lentiviral vectors for gene therapy of hemophilia a
VUBIR (Vrije Universiteit Brussel)·2007
Vaccination of Colorectal Cancer Patients with Modified Vaccinia Ankara Encoding the Tumor Antigen 5T4 (TroVax) Given Alongside Chemotherapy Induces Potent Immune Responses
Clinical Cancer Research·2007· 90 citedOpen Access
Assays for the Quality Control of Lentiviral Vectors
2007· 1 cited
Factors that influence VSV‐G pseudotyping and transduction efficiency of lentiviral vectors—<i>in vitro</i> and <i>in vivo</i> implications
The Journal of Gene Medicine·2007· 30 cited
The integration profile of EIAV-based vectors
Molecular Therapy·2006· 47 citedOpen Access
Vaccination of Colorectal Cancer Patients with Modified Vaccinia Ankara Delivering the Tumor Antigen 5T4 (TroVax) Induces Immune Responses which Correlate with Disease Control: A Phase I/II Trial
Clinical Cancer Research·2006· 167 cited
830. Determination of the Profile and Site Preference of Lentiviral Vector Integration In Vivo
Molecular Therapy·2006Open Access
Lentivirus-Mediated Gene Transfer to the Central Nervous System: Therapeutic and Research Applications
Human Gene Therapy·2006· 183 cited
Retinoic acid receptor β2 promotes functional regeneration of sensory axons in the spinal cord
Nature Neuroscience·2005· 122 cited
Lentivirus-Mediated Gene Transfer to the Central Nervous System: Therapeutic and Research Applications
Human Gene Therapy·2005· 6 cited
Active treatment of murine tumors with a highly attenuated vaccinia virus expressing the tumor associated antigen 5T4 (TroVax) is CD4+ T cell dependent and antibody mediated
Cancer Immunology Immunotherapy·2005· 47 citedOpen Access
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Frequent Co-authors

Alan J. Kingsman(28), Kyriacos Mitrophanous(13), Nicholas D. Mazarakis(12), Mimoun Azzouz(8), Melanie J. Dobson(7), Jane Mellor(7), Mick F. Tuite(6), G. Ralph(5), Martin Braddock(5), Sally E. Adams(5), Liang‐Fong Wong(4), Richard Harrop(4), Stuart Naylor(4), Nigel Roberts(4), Wilma Wilson(4), A J Kingsman(4), Clive A. Stanway(4), Alistair Chambers(4), Paula M. Cannon(3), Lucy E. Walmsley(3)