Kyriacos Mitrophanous

Oxford BioMedica (United Kingdom) — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index5.6kcitations109works2.62yr avg
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Research Topics

Virus-based gene therapy research(58), CRISPR and Genetic Engineering(24), Viral Infectious Diseases and Gene Expression in Insects(20), RNA Interference and Gene Delivery(15), CAR-T cell therapy research(12)

Publications109 total

Enhanced transcriptional insulation of lentiviral vectors using “sequence-upgraded polyA long terminal repeats” or “supA-LTRs”
Molecular Therapy Advances·2025
Normothermic perfusion of human livers for profiling lentiviral vector pharmacokinetics and transduction
Molecular Therapy Advances·2025Open Access
Risks of replication-competent retro/lentivirus from associated vector systems: Is it time for a roadmap toward reduced testing?
Molecular Therapy — Methods & Clinical Development·2025· 3 citedOpen Access
Improved production and quality of lentiviral vectors by major-splice-donor mutation and co-expression of a novel U1 snRNA-based enhancer
Heliyon·2025· 1 citedOpen Access
Efficient in vivo generation of CAR T cells using a retargeted fourth-generation lentiviral vector
Molecular Therapy·2025· 8 citedOpen Access
Membrane adsorber design for lentiviral vector recovery
Molecular Therapy — Methods & Clinical Development·2025· 2 citedOpen Access
Deep brain stimulation is well tolerated and effective following ProSavin® gene therapy for Parkinson's disease
Neurotherapeutics·2025· 1 citedOpen Access
Enhancing titers of therapeutic lentiviral vectors using PKC agonists
Molecular Therapy — Methods & Clinical Development·2025· 4 citedOpen Access
Gender difference in pre-clinical liver-directed gene therapy with lentiviral vectors
Experimental Biology and Medicine·2025· 1 citedOpen Access
Abstract A014: Autologous anti-5T4 CAR-T cell culture with live patient tumor slices reveals T cell intrinsic and microenvironmental suppression in pancreatic ductal adenocarcinoma
Cancer Immunology Research·2025
Data from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
Supplementary Figure 2 from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
Supplementary Table 2 from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
Supplementary Figure 4 from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
Supplementary Table 1 from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
Supplementary Figure 3 from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
Supplementary Figure 1 from Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
2025Open Access
What is the <i>real</i> value of omics data? Enhancing research outcomes and securing long-term data excellence
Nucleic Acids Research·2024· 16 citedOpen Access
Targeting Tumor Antigen 5T4 Using CAR T Cells for the Treatment of Acute Myeloid Leukemia
Molecular Cancer Therapeutics·2024· 4 cited
Auto‐transduction in lentiviral vector bioprocessing: A quantitative assessment and a novel inhibition strategy
Biotechnology and Bioengineering·2024· 3 citedOpen Access
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Frequent Co-authors

Susan M. Kingsman(21), James Miskin(15), Nicholas D. Mazarakis(14), G. Ralph(11), Mimoun Azzouz(8), Michelle Kelleher(8), Pippa A. Radcliffe(7), Scott Ellis(7), Liang‐Fong Wong(6), Alan J. Kingsman(6), Hannah J. Stewart(6), Stéphane Palfi(5), Philippe Hantraye(5), Fiona M. Ellard(5), Katie Binley(5), Julie Loader(5), Laura J. McCloskey(5), Lee Davies(5), Carol Knevelman(5), Lucy E. Walmsley(4)