Radovan Dvorský

Heinrich Heine University Düsseldorf — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

34h-index4.8kcitations85works3.72yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(38), Protein Tyrosine Phosphatases(9), Cellular transport and secretion(8), Enzyme Structure and Function(8), Receptor Mechanisms and Signaling(7)

Publications85 total

Structural and functional insights into the p160 Rho-associated coiled-coil-containing protein kinase ROCK
2026Open Access
SIRT4 as a novel interactor and candidate suppressor of C-RAF kinase in MAPK signaling
Life Science Alliance·2024· 3 citedOpen Access
Functional Classification and Interaction Selectivity Landscape of the Human SH3 Domain Superfamily
Cells·2024· 8 citedOpen Access
Functional Classification and Interaction Selectivity Landscape of the Human SH3 Domain Superfamily
Preprints.org·2023· 2 citedOpen Access
Identification of SIRT4 as a novel paralog-specific interactor and candidate suppressor of C-RAF kinase in MAPK signaling
2023Open Access
A Systematic Compilation of Human SH3 Domains: A Versatile Superfamily in Cellular Signaling
Cells·2023· 34 citedOpen Access
Molecular analyses of the C-terminal CRAF variants associated with cardiomyopathy reveal their opposing impacts on the active conformation of the kinase domain
Journal of Biomolecular Structure and Dynamics·2023· 3 cited
Molecular analyses of the C-terminal CRAF variants associated with cardiomyopathy reveal their opposing impacts on the active conformation of the kinase domain
Figshare·2023Open Access
New mechanistic insights into the RAS-SIN1 interaction at the membrane
Frontiers in Cell and Developmental Biology·2022· 9 citedOpen Access
CDC42-IQGAP Interactions Scrutinized: New Insights into the Binding Properties of the GAP-Related Domain
International Journal of Molecular Sciences·2022· 6 citedOpen Access
Selectivity Determinants of RHO GTPase Binding to IQGAPs
International Journal of Molecular Sciences·2021· 18 citedOpen Access
Electrostatic Forces Mediate the Specificity of RHO GTPase-GDI Interactions
International Journal of Molecular Sciences·2021· 11 citedOpen Access
Selective inhibition of IL-6 trans-signaling by a miniaturized, optimized chimeric soluble gp130 inhibits T <sub>H</sub> 17 cell expansion
Science Signaling·2021· 25 cited
The intramolecular allostery of GRB2 governing its interaction with SOS1 is modulated by phosphotyrosine ligands
Biochemical Journal·2021· 25 citedOpen Access
ω‐Imidazolyl‐alkyl derivatives as new preclinical drug candidates for treating non‐alcoholic steatohepatitis
Physiological Reports·2021· 1 citedOpen Access
A comprehensive analysis of RAS-effector interactions reveals interaction hotspots and new binding partners
Journal of Biological Chemistry·2021· 25 citedOpen Access
A New CYP2E1 Inhibitor, 12‐Imidazolyl‐1‐dodecanol, Represents a Potential Treatment for Hepatocellular Carcinoma
Canadian Journal of Gastroenterology and Hepatology·2021· 8 citedOpen Access
Drug targeting CYP2E1 for the treatment of early-stage alcoholic steatohepatitis
PLoS ONE·2020· 30 citedOpen Access
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function
The Journal of Experimental Medicine·2019· 191 citedOpen Access
ω-imidazolyl-alkyl derivatives as new preclinical drug candidates for NASH therapy
2019Open Access
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Frequent Co-authors

Mohammad Reza Ahmadian(39), Ehsan Amin(9), Lothar Gremer(8), Martin Zenker(8), Ion Cristian Cirstea(7), Saeideh Nakhaei‐Rad(6), Mamta Jaiswal(6), Francesca Pantaleoni(5), Marco Tartaglia(5), Kazem Nouri(5), Eyad K. Fansa(5), Neda S. Kazemein Jasemi(5), Francesca Romana Lepri(4), Oliver H.F. Krumbach(4), Dennis Fiegen(4), Lars Blumenstein(4), Soheila Rezaei Adariani(4), Gerhard Fritz(3), Raja Atreya(3), Markus F. Neurath(3)