Aileen Boyle

Roslin Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index792citations15works0.02yr avg
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Research Topics

Prion Diseases and Protein Misfolding(14), Neurological diseases and metabolism(4), Trace Elements in Health(2), Alzheimer's disease research and treatments(1), Neuroinflammation and Neurodegeneration Mechanisms(1)

Publications15 total

TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease
Frontiers in Neuroscience·2025Open Access
Conservation of vCJD Strain Properties After Extraction and In Vitro Propagation of PrPSc from Archived Formalin-Fixed Brain and Appendix Tissues Using Highly Sensitive Protein Misfolding Cyclic Amplification
Molecular Neurobiology·2023Open Access
No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease
Emerging infectious diseases·2020· 7 citedOpen Access
Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes
Brain·2019· 28 citedOpen Access
Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case
Emerging infectious diseases·2017· 5 citedOpen Access
Strain Typing of Prion Diseases Using In Vivo Mouse Models
Methods in molecular biology·2017· 9 cited
The Glycosylation Status of PrP <sup>C</sup> Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species
Journal of Virology·2015· 56 citedOpen Access
Variably Protease-Sensitive Prionopathy, a Unique Prion Variant with Inefficient Transmission Properties
Emerging infectious diseases·2014· 67 citedOpen Access
Variant CJD
Prion·2014· 100 citedOpen Access
Variable protease-sensitive prionopathy; a unique prion variant with inefficient transmission properties
Prion·2014· 1 cited
Transmissions of variant Creutzfeldt–Jakob disease from brain and lymphoreticular tissue show uniform and conserved bovine spongiform encephalopathy-related phenotypic properties on primary and secondary passage in wild-type mice
Journal of General Virology·2009· 72 cited
Molecular and biological strain typing of sporadic and variant Creutzfeldt-Jakob disease
Prion·2006
Efficient Transmission and Characterization of Creutzfeldt–Jakob Disease Strains in Bank Voles
PLoS Pathogens·2006· 230 citedOpen Access
TSE Strain Typing in Mice
Birkhäuser Basel eBooks·2004· 8 cited
Strain characterization of natural sheep scrapie and comparison with BSE
Journal of General Virology·2002· 209 cited

Frequent Co-authors

Abigail B. Diack(9), Jean Manson(9), James W. Ironside(6), Diane Ritchie(6), Moira E. Bruce(5), Robert Will(4), Pedro Piccardo(4), I. McConnell(3), Mark Head(3), Richard Knight(3), Deborah Brown(3), Alexander Peden(2), Laura Morabito(2), David H. MacLennan(2), Paul S. Burgoyne(2), Chris Plinston(2), Romolo Nonno(1), Michele Angelo Di Bari(1), Franco Cardone(1), Gabriele Vaccari(1)