Valentina Vavassori

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index937citations20works10.32yr avg
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Research Topics

Virus-based gene therapy research(10), CAR-T cell therapy research(10), CRISPR and Genetic Engineering(9), Cytomegalovirus and herpesvirus research(3), Mesenchymal stem cell research(2)

Publications20 total

Insights from an extensive multi-step multi-stakeholder engagement in circular bio-based economy
Open Research Europe·2025Open Access
EDUCATIONAL GAMES FOR BIOECONOMY LEARNING: INSIGHTS FROM THE HORIZON EUROPE GENB PROJECT
INTED proceedings·2025
TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells
Frontiers in Immunology·2024· 21 citedOpen Access
Exonic knockout and knockin gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency
Science Translational Medicine·2024· 20 citedOpen Access
Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of <scp> CD4 <sup>+</sup> </scp> T‐cells for the treatment of Hyper <scp>IgM1</scp>
The EMBO Journal·2023· 9 citedOpen Access
Archives and the environment report
2023Open Access
Scalable GMP-compliant gene correction of CD4+ T cells with IDLV template functionally validated in vitro and in vivo
Molecular Therapy — Methods & Clinical Development·2023· 9 citedOpen Access
P1405: IN-DEPTH GENOME INTEGRITY EVALUATION AND GMP-COMPLIANT MANUFACTURING OF HDR GENE EDITED CD4+ T CELLS FOR THE TREATMENT OF HYPER IGM 1
HemaSphere·2023Open Access
Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells
Blood·2023· 66 citedOpen Access
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells
Cell stem cell·2022· 120 citedOpen Access
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs
Molecular Therapy·2022· 6 citedOpen Access
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs
Molecular Therapy·2022· 16 citedOpen Access
Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells
Cell·2022· 54 citedOpen Access
Networking the Archive: The Stories and Structures of Thos. Agnew's Stock Books
Journal on Computing and Cultural Heritage·2022· 3 cited
Towards Clinical Translation of Hematopoietic Cell Gene Editing for Treating Hyper-IgM Type 1
Blood·2021
Gene Editing of Hematopoietic Stem Cells: Hopes and Hurdles Toward Clinical Translation
Frontiers in Genome Editing·2021· 41 citedOpen Access
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome
EMBO Molecular Medicine·2021· 49 citedOpen Access
Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking
Nature Biotechnology·2020· 195 citedOpen Access
Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
Cell stem cell·2019· 328 cited
Generation of Memory Stem T Cells Specific for Tumor Antigens and Resistant to Inhibitory Signals By Genome Editing
Blood·2018

Frequent Co-authors

Luigi Naldini(15), Samuele Ferrari(12), Pietro Genovese(10), Aurélien Jacob(9), Ivan Merelli(9), Luisa Albano(8), Daniele Canarutto(8), Anna Villa(7), Stefano Beretta(6), Raffaella Di Micco(5), Maria Carmina Castiello(5), Claudia Asperti(5), Marina Radrizzani(5), Anastasia Conti(4), Chiara Brombin(4), Angelica Varesi(4), Simona Porcellini(4), Lucia Sergi Sergi(4), Federica Cugnata(3), Vassilios Lougaris(3)