Jurgen Kriel

Walter and Eliza Hall Institute of Medical Research — Australia

Medicine · Health Sciences

7h-index447citations28works1.42yr avg
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Research Topics

Autophagy in Disease and Therapy(11), Glioma Diagnosis and Treatment(5), Mitochondrial Function and Pathology(5), Bioinformatics and Genomic Networks(3), Single-cell and spatial transcriptomics(3)

Publications28 total

An integrative spatial multi-omic workflow for unified analysis of tumor tissue
Cell Reports Methods·2026Open Access
EPCO-27. SMINT AND SPAMTP: INTEGRATIVE SPATIAL ANALYSIS TOOLS REVEAL METABOLIC AND TRANSCRIPTIONAL DRIVERS OF INVASION IN IDH-MUTATED GLIOMA
Neuro-Oncology·2025Open Access
Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial
Nature Medicine·2025· 3 citedOpen Access
Correlative 3D imaging method for analysing lesion architecture in susceptible mice infected with <i>Mycobacterium tuberculosis</i>
Disease Models & Mechanisms·2025· 2 citedOpen Access
Spatial omics shed light on the tumour organisation of glioblastoma
Seminars in Cell and Developmental Biology·2025· 5 citedOpen Access
Antisecretory Factor 16 (AF16): A Promising Avenue for the Treatment of Traumatic Brain Injury—An In Vitro Model Approach
Journal of Molecular Neuroscience·2024· 1 citedOpen Access
An integrative spatial multi-omic workflow for unified analysis of tumor tissue
2024· 2 cited
An integrative spatial multi-omic workflow for unified analysis of tumor tissue
2024· 3 citedOpen Access
OS07.5.A MULTI-MODAL EXAMINATION OF SPATIAL HETEROGENEITY IN THE ASTROCYTOMA MICROENVIRONMENT
Neuro-Oncology·2024Open Access
Applying volumetric electron microscopy to visualize xylem tissue impacted by citrus tristeza virus-induced stem pitting
Journal of Citrus Pathology·2024· 1 citedOpen Access
<i>Mycobacterium tuberculosis</i> ESX-T7SS impacts the 3D architecture of tuberculous lesion in susceptible mice
2024Open Access
Autophagy‐induced cell death by aqueous and polyphenol‐enriched extracts of honeybush (<i>Cyclopia</i> spp.) in liver and colon cancer cells
Food Science & Nutrition·2024· 1 citedOpen Access
Abstract 5498: Multi-modal examination of spatial heterogeneity in the astrocytoma microenvironment
Cancer Research·2024
5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma
Biochemistry and Biophysics Reports·2024· 1 citedOpen Access
Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV
PLoS Genetics·2023· 7 citedOpen Access
The Highs and Lows of Memantine—An Autophagy and Mitophagy Inducing Agent That Protects Mitochondria
Cells·2023· 6 citedOpen Access
Spatial architecture of high-grade glioma reveals tumor heterogeneity within distinct domains
Neuro-Oncology Advances·2023· 47 citedOpen Access
Neurexin 2 p.G849D variant, implicated in Parkinson’s disease, increases reactive oxygen species, and reduces cell viability and mitochondrial membrane potential in SH-SY5Y cells
Journal of Neural Transmission·2022· 6 cited
Investigating the Role of Spermidine in a Model System of Alzheimer’s Disease Using Correlative Microscopy and Super-resolution Techniques
Frontiers in Cell and Developmental Biology·2022· 21 citedOpen Access
Correlative Light and Electron Microscopy (CLEM): Bringing Together the Best of Both Worlds to Study Neuronal Autophagy
Neuromethods·2021· 3 cited
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Frequent Co-authors

Ben Loos(14), Joel J D Moffet(9), James R. Whittle(9), Saskia Freytag(9), Sarah A. Best(9), Lize Engelbrecht(5), Tianyao Lu(5), Vinod K. Narayana(5), Ebenezer O. Fatunla(4), Adam Valkovic(4), Lutz Freytag(3), Rensu P. Theart(3), Malcolm J. McConville(3), Ellen Tsui(3), Oluwaseun E. Fatunla(2), Jordan Jones(2), Samuel Roberts-Thomson(2), Dumisile Lumkwana(2), Christopher J. Peddie(2), Lucy Collinson(2)