C Winkler

Medicine · Health Sciences

15h-index919citations86works10.02yr avg
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Research Topics

Cardiac Imaging and Diagnostics(16), Medical Imaging and Pathology Studies(10), DNA Repair Mechanisms(6), Advanced MRI Techniques and Applications(6), Lung Cancer Diagnosis and Treatment(5)

Publications85 total

Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response
British Journal of Cancer·2021· 46 citedOpen Access
SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in high-grade serous ovarian cancer
JCI Insight·2021· 36 citedOpen Access
SLFN11 informs on standard of care and novel treatments in a wide range of cancer models
British Journal of Cancer·2020· 68 citedOpen Access
SLFN11 captures cancer-immunity interactions associated with platinum sensitivity in ovarian cancer
2020Open Access
Trends und Ausblick
2020· 1 cited
DO MULTI-GRIP HANDS INCREASE FUNCTION AND PATIENT SATISFACTION WHEN COMPARED TO TRADITIONAL MYOELECTRIC HANDS?
Canadian Prosthetics & Orthotics Journal·2018· 3 citedOpen Access
A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Journal of Biological Chemistry·2018· 50 citedOpen Access
Overexpression of PP1–NIPP1 limits the capacity of cells to repair DNA double-strand breaks
Journal of Cell Science·2018· 18 citedOpen Access
The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis
Scientific Reports·2017· 17 citedOpen Access
The selective inhibition of protein phosphatase-1 results in mitotic catastrophe and impaired tumor growth
Journal of Cell Science·2015· 36 citedOpen Access
PP1-NIPP1 dephosphorylates and destabilizes a subset of Cdk substrates that are essential for homologous recombination repair
2015
Comparative Label-Free Mass Spectrometric Analysis of Mildly versus Severely Affected mdx Mouse Skeletal Muscles Identifies Annexin, Lamin, and Vimentin as Universal Dystrophic Markers
Molecules·2015· 48 citedOpen Access
The inhibition of protein phosphatase-1 induces cancer cell death through mitotic catastrophe
2015
Protein phosphatase PP1‐NIPP1 activates mesenchymal genes in HeLa cells
FEBS Letters·2015· 15 cited
PP1-NIPP1 contributes to cell-cyle progression by dephosphorylation of a subset of Cdk substrates
2014
Cell-cycle defects following deregulation of the protein phosphatase -1 interactor NIPP1
2014
Early Remodeling of Perinuclear Ca <sup>2+</sup> Stores and Nucleoplasmic Ca <sup>2+</sup> Signaling During the Development of Hypertrophy and Heart Failure
Circulation·2014· 84 citedOpen Access
MRI Plaque Imaging Detects Carotid Plaques with a High Risk for Future Cerebrovascular Events in Asymptomatic Patients
PLoS ONE·2013· 50 citedOpen Access
4D-networking by mitotic phosphatases
Current Opinion in Cell Biology·2013· 33 cited
Overexpression of the NIPP1-PP1 holoenzyme causes replication stress in cervical cancer cells
2013
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Frequent Co-authors

R. Félix(9), Mathieu Bollen(8), Aleyde Van Eynde(6), P. Thurn(5), Monique Beullens(4), W. Pensky(4), A Schaede(4), H. J. Biersack(4), Elisabetta Leo(3), Bart Lesage(3), Shannah Boens(3), M. Thelen(3), H.-P. Breuel(3), Gemma N. Jones(2), Tarrion Baird(2), Andrew J. Pierce(2), Tobias Saam(2), Jaroslav Pelisek(2), P. Heider(2), Angelina Bockelbrink(2)