Aleyde Van Eynde

KU Leuven — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index5.0kcitations93works2.72yr avg
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Research Topics

Epigenetics and DNA Methylation(22), RNA Research and Splicing(15), RNA modifications and cancer(12), Protein Tyrosine Phosphatases(12), Microtubule and mitosis dynamics(10)

Publications93 total

Liver knock-out of nuclear inhibitor of protein phosphatase-1 in mice decreases hepatic iron
Blood·2025Open Access
The nuclear-cytoplasmic ratio controls the cell-cycle period in compartmentalized frog egg extract
Current Biology·2025· 3 citedOpen Access
PPP1R2 stimulates protein phosphatase-1 through stabilisation of dynamic subunit interactions
Nature Communications·2024· 3 citedOpen Access
The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract
2024· 4 citedOpen Access
SDS22 coordinates the assembly of holoenzymes from nascent protein phosphatase-1
Nature Communications·2024· 6 citedOpen Access
Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice
Journal of Investigative Dermatology·2024Open Access
<scp>DNA</scp> damage‐induced allosteric activation of protein phosphatase <scp>PP1</scp> : <scp>NIPP1</scp> through Src kinase‐induced circularization of <scp>NIPP1</scp>
FEBS Journal·2024· 3 citedOpen Access
Author response for "&lt;scp&gt;DNA&lt;/scp&gt; damage‐induced allosteric activation of protein phosphatase &lt;scp&gt;PP1&lt;/scp&gt;:&lt;scp&gt;NIPP1&lt;/scp&gt; through Src kinase‐induced circularization of &lt;scp&gt;NIPP1&lt;/scp&gt;"
2023
Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases
Nature Communications·2021· 150 citedOpen Access
Source Data
Figshare·2021· 1 citedOpen Access
Source Data
Figshare·2021Open Access
Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1
Oncogenesis·2020· 10 citedOpen Access
Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation
Journal of Investigative Dermatology·2020· 7 citedOpen Access
Correction: MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells
Bioscience Reports·2018· 2 citedOpen Access
The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2
Journal of Biological Chemistry·2018· 15 citedOpen Access
A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Journal of Biological Chemistry·2018· 50 citedOpen Access
Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2018· 56 citedOpen Access
Overexpression of PP1–NIPP1 limits the capacity of cells to repair DNA double-strand breaks
Journal of Cell Science·2018· 18 citedOpen Access
The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis
Scientific Reports·2017· 17 citedOpen Access
Withdrawal: Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.
Journal of Biological Chemistry·2017· 6 citedOpen Access
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Frequent Co-authors

Mathieu Bollen(50), Monique Beullens(35), Willy Stalmans(19), Shannah Boens(9), Lijs Beke(7), Bart Lesage(6), Nele Van Dessel(6), Veerle Vulsteke(6), Janina Görnemann(6), Mónica Ferreira(6), Iris Verbinnen(6), Mieke Nuytten(5), C Winkler(5), Kathelijne Szekér(5), Hugo Ceulemans(4), Izabela Jagiełło(4), Stefaan Keppens(4), Stefaan Wera(3), An Boudrez(3), Rita Derua(3)