Cynthia M. Arokiaraj

University of Pittsburgh — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index761citations24works8.02yr avg
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Research Topics

Virus-based gene therapy research(11), Pain Mechanisms and Treatments(6), RNA Interference and Gene Delivery(6), CRISPR and Genetic Engineering(4), RNA regulation and disease(4)

Publications24 total

Combining Machine Learning and Multiplexed, <i>In Situ</i> Profiling to Engineer Cell Type and Behavioral Specificity
2025· 2 citedOpen Access
Spatial, transcriptomic, and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition
Cell Reports·2024· 14 citedOpen Access
Human cell surface-AAV interactomes identify LRP6 as blood-brain barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder
Nature Communications·2024· 13 citedOpen Access
Human cell surface-AAV interactomes identify LRP6 as blood-brain-barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder
2024· 3 citedOpen Access
Alleviation of neuropathic pain with neuropeptide Y requires spinal Npy1r interneurons that coexpress Grp
JCI Insight·2023· 15 citedOpen Access
Next-generation sequencing of AAV.CAP-Mac from Chuapoco et al. (2023) Nature Nanotechnology
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Next-generation sequencing of AAV.CAP-Mac from Chuapoco et al. (2023) Nature Nanotechnology
2023Open Access
Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
Nature Nanotechnology·2023· 108 citedOpen Access
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates
Nature Communications·2023· 81 citedOpen Access
Intravenous functional gene transfer throughout the brain of non-human primates using AAV
2023· 3 citedOpen Access
Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates
2023· 13 citedOpen Access
Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system
Current Research in Neurobiology·2023· 44 citedOpen Access
List of contributors
Elsevier eBooks·2022
Spinal interneurons and pain
Elsevier eBooks·2022
Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems
Neuron·2022· 122 citedOpen Access
Spatial, transcriptomic and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition
2022· 4 citedOpen Access
Intravenous gene transfer throughout the brain of infant Old World primates using AAV
2022· 19 citedOpen Access
Multiplex In Situ Hybridization of the Primate and Rodent DRG and Spinal Cord
Neuromethods·2022· 3 cited
Use of Intraspinally Delivered Chemogenetic Receptor, PSAM-GlyR, to Probe the Behavioral Role of Spinal Dorsal Horn Neurons
Neuromethods·2022· 2 cited
Engineered AAVs for Non-Invasive Functional Transgene Expression in Rodent and Non-Human Primate Central and Peripheral Nervous Systems
SSRN Electronic Journal·2022· 3 citedOpen Access
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Frequent Co-authors

Viviana Gradinaru(12), Xinhong Chen(11), Rebecca P. Seal(10), Lillian Campos(10), Andrew S. Fox(10), Cory T. Miller(8), Miguel R. Chuapoco(8), Myung‐chul Noh(7), Timothy F. Shay(7), Damien A. Wolfe(6), Nick Goeden(6), John K. Mich(6), Bryan B. Gore(6), Naz Taskin(6), Natalie Weed(6), Jonathan T. Ting(6), Nicholas C. Flytzanis(5), J. Christopher Octeau(5), Ken Y. Chan(5), J Scherrer(5)