J R Nevins

Howard Hughes Medical Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index1.8kcitations11works0.02yr avg
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Research Topics

Virus-based gene therapy research(7), Cancer-related Molecular Pathways(4), RNA Interference and Gene Delivery(4), Viral Infectious Diseases and Gene Expression in Insects(3), RNA modifications and cancer(2)

Publications11 total

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
Nature·1997· 468 cited
Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function
Nature Medicine·1996· 72 cited
Ectopic E2F expression induces S phase and apoptosis in Drosophila imaginal discs.
Genes & Development·1996· 150 citedOpen Access
Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A.
Proceedings of the National Academy of Sciences·1994· 68 citedOpen Access
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A
Cell·1991· 374 cited
An adenovirus E4 gene product trans-activates E2 transcription and stimulates stable E2F binding through a direct association with E2F.
Proceedings of the National Academy of Sciences·1990· 108 citedOpen Access
Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system.
Proceedings of the National Academy of Sciences·1989· 106 citedOpen Access
Mechanisms of Viral-Mediated Trans-Activation of Transcription
Advances in virus research·1989· 57 cited
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.
Proceedings of the National Academy of Sciences·1987· 287 citedOpen Access
Sequences and factors controlling adenovirus gene expression
1985
Localization of the adenovirus E1Aa protein, a positive-acting transcriptional factor, in infected cells infected cells.
Molecular and Cellular Biology·1983· 97 cited

Frequent Co-authors

Gustavo Leone(1), James DeGregori(1), Rosalie C. Sears(1), Laszlo Jakoi(1), Maria Mudryj(1), Stephen H. Devoto(1), Scott W. Hiebert(1), Tony Hunter(1), Jonathon Pines(1), Imre Kovesdi(1), Ronald R. Reichel(1), Maki Asano(1), Robin P. Wharton(1), S D Neill(1), Catharina Hemström(1), Anders Virtanen(1), Srilata Bagchi(1), Pradip Raychaudhuri(1), L T Feldman(1), Jun Ishizaki(1)