Robert L. Houtz

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index3.0kcitations83works0.02yr avg
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Research Topics

Cancer-related gene regulation(27), Epigenetics and DNA Methylation(19), RNA modifications and cancer(18), Photosynthetic Processes and Mechanisms(15), Peptidase Inhibition and Analysis(8)

Publications83 total

Isolated spinach ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit .sup..epsilon. N-methyltransferase and method of inactivating ribulose-1,5-bisphosphatase carboxylase/oxygenase large subunit .sup..epsilon. N-methyltransferase activity
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)·2023Open Access
Isolated spinach ribulose-1,5-bisphosphate carboxylase/oxgenase large subunit .epsilon. n-methyltransferase and method of inactivating ribulose-1,5-bishosphatase .epsilon. n-methyltransferase activity
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)·2023Open Access
Development and Characterization of a Model Post‐Translationsally Modified Protein Library
The FASEB Journal·2018
The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7
Journal of Biological Chemistry·2016· 24 citedOpen Access
Post-translational modifications in the large subunit of ribulose bisphosphate carboxylase/oxygenase (N-terminal acetylation/trimethyllysine/fast-atom bombardment/mass spectrometry)
2016
Sulfur–Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9
ACS Chemical Biology·2015· 113 cited
Calmodulin Methyltransferase Is Required for Growth, Muscle Strength, Somatosensory Development and Brain Function
PLoS Genetics·2015· 21 citedOpen Access
Manipulating Unconventional CH-Based Hydrogen Bonding in a Methyltransferase via Noncanonical Amino Acid Mutagenesis
ACS Chemical Biology·2014· 26 cited
An Intergenic Region Shared by At4g35985 and At4g35987 in Arabidopsis thaliana Is a Tissue Specific and Stress Inducible Bidirectional Promoter Analyzed in Transgenic Arabidopsis and Tobacco Plants
PLoS ONE·2013· 60 citedOpen Access
Calmodulin-Mediated Signal Transduction Pathways in Arabidopsis Are Fine-Tuned by Methylation
The Plant Cell·2013· 35 citedOpen Access
Conservation and Functional Importance of Carbon–Oxygen Hydrogen Bonding in AdoMet-Dependent Methyltransferases
Journal of the American Chemical Society·2013· 101 cited
Human Calmodulin Methyltransferase: Expression, Activity on Calmodulin, and Hsp90 Dependence
PLoS ONE·2012· 13 citedOpen Access
Mechanism and Significance of Post-Translational Modifications in the Large (LS) and Small (SS) Subunits of Ribulose-1,5 Bisphosphate Carboxylase/Oxygenase
2012Open Access
Utilization of a calmodulin lysine methyltransferase co-expression system for the generation of a combinatorial library of post-translationally modified proteins
Protein Expression and Purification·2012· 14 citedOpen Access
Modified Rubisco Large Subunit N-Methyltransferase Useful for Targeting Molecules to the Active-Site Vicinity of Ribulose-1,5-Bisphosphate
UKnowledge (University of Kentucky)·2012Open Access
Advancing Our Understanding and Capacity to Engineer Nature’s CO2-Sequestering Enzyme, Rubisco 
PLANT PHYSIOLOGY·2010· 449 citedOpen Access
SET7/9 Catalytic Mutants Reveal the Role of Active Site Water Molecules in Lysine Multiple Methylation
Journal of Biological Chemistry·2010· 61 citedOpen Access
Calmodulin methyltransferase is an evolutionarily conserved enzyme that trimethylates Lys-115 in calmodulin
Nature Communications·2010· 77 citedOpen Access
Molecular Mechanisms of Lysine Methylation
The FASEB Journal·2010
SET7/9 Y245A in complex with TAF10-K189me3 peptide and AdoHcy
2010
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Frequent Co-authors

Lynnette M.A. Dirk(16), Raymond C. Trievel(12), Roberta Magnani(8), R. Michael Mulligan(4), Mark A. Williams(4), Scott Horowitz(3), Steve Scheiner(3), Jean‐François Couture(3), N. E. Tolbert(3), S. K. Ries(3), Nihar R. Nayak(3), Malcolm Royer(3), Spencer M. Whitney(2), James H. Hurley(2), E. Megan Flynn(2), J.S. Brunzelle(2), Ross O. Nable(2), George M. Cheniae(2), Upendra Adhikari(2), Ryan A. Mehl(2)