Tim Vervliet

Cellular Research (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index4.6kcitations66works21.12yr avg
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Research Topics

Cell death mechanisms and regulation(16), Autophagy in Disease and Therapy(13), Endoplasmic Reticulum Stress and Disease(13), Calcium signaling and nucleotide metabolism(12), Mitochondrial Function and Pathology(11)

Publications65 total

CISD2 ensures adequate ER-mitochondrial coupling, critically supporting mitochondrial function in neurons
Acta Neuropathologica Communications·2025Open Access
An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins
Journal of Cachexia Sarcopenia and Muscle·2025Open Access
Cisd2 ensures adequate ER-mitochondrial coupling, thereby critically supporting mitochondrial function in neurons
2025Open Access
The BCL2 family: from apoptosis mechanisms to new advances in targeted therapy
Signal Transduction and Targeted Therapy·2025· 165 citedOpen Access
Inactive ryanodine receptors sustain lysosomal availability for autophagy by promoting ER-lysosomal contact site formation
2024· 1 citedOpen Access
CISD2 counteracts the inhibition of ER-mitochondrial calcium transfer by anti-apoptotic BCL-2
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2024· 9 citedOpen Access
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
Acta Neuropathologica Communications·2024· 5 citedOpen Access
ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome
Nature Communications·2024· 40 citedOpen Access
Correction to: Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs
Acta Neuropathologica·2024Open Access
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
2024Open Access
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs
Acta Neuropathologica·2024· 12 citedOpen Access
ER Calcium Depletion as a Key Driver for Impaired ER-to-Mitochondria Calcium Transfer and Mitochondrial Dysfunction in Wolfram Syndrome
2023· 1 citedOpen Access
A facile method to generate cerebral organoids from human pluripotent stem cells
PubMed·2023· 2 citedOpen Access
Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer’s disease
IBRO Neuroscience Reports·2023· 12 citedOpen Access
Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2
Journal of Cell Science·2022· 6 citedOpen Access
Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression
Frontiers in Cell and Developmental Biology·2022· 38 citedOpen Access
The alkalinizing, lysosomotropic agent ML-9 induces a pH-dependent depletion of ER Ca2+ stores in cellulo
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2022· 3 citedOpen Access
Long-Term Culture of Patient-Derived Cardiac Organoids Recapitulated Duchenne Muscular Dystrophy Cardiomyopathy and Disease Progression
2022· 2 citedOpen Access
Cardiomyocyte differentiation from iPS cells is delayed following knockout of Bcl-2
2022· 1 citedOpen Access
Uniting the divergent Wolfram syndrome–linked proteins WFS1 and CISD2 as modulators of Ca<sup>2+</sup>signaling
Science Signaling·2021· 32 citedOpen Access
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Frequent Co-authors

Geert Bultynck(41), Jan B. Parys(22), Ludwig Missiaen(8), Humbert De Smedt(7), Giovanni Monaco(7), Hristina Ivanova(6), Catherine M. Verfaillie(6), Jens Loncke(6), Luc Leybaert(5), Rita La Rovere(5), Santeri Kiviluoto(5), Robin Duelen(5), Maurilio Sampaolesi(5), Yoke Chin Chai(5), Elke Decrock(4), Tomas Luyten(4), Allen Kaasik(4), Martijn Kerkhofs(4), Manon Callens(3), Haidar Akl(3)