Roger G. Pertwee

University of Aberdeen — United Kingdom

Medicine · Health Sciences

96h-index43.1kcitations375works1.52yr avg
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Research Topics

Cannabis and Cannabinoid Research(302), Neuroscience and Neuropharmacology Research(113), Neurotransmitter Receptor Influence on Behavior(109), Sleep and Wakefulness Research(52), Forensic Toxicology and Drug Analysis(38)

Publications373 total

A Tourette Syndrome/ADHD-like Phenotype Results from Postnatal Disruption of CB1 and CB2 Receptor Signalling
International Journal of Molecular Sciences·2025· 2 citedOpen Access
Cannabinoid receptors in GtoPdb v.2025.1
IUPHAR/BPS Guide to Pharmacology CITE·2025· 1 citedOpen Access
Cannabinoid receptors in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE·2023· 3 citedOpen Access
The Plant Derived 3-3′-Diindolylmethane (DIM) Behaves as CB2 Receptor Agonist in Prostate Cancer Cellular Models
International Journal of Molecular Sciences·2023· 8 citedOpen Access
M3 Receptor Pathway Stimulates Rapid Transcription of the CB1 Receptor Activation through Calcium Signalling and the CNR1 Gene Promoter
International Journal of Molecular Sciences·2023· 5 citedOpen Access
Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593
Frontiers in Pharmacology·2022· 7 citedOpen Access
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R)
Frontiers in Chemistry·2022· 16 citedOpen Access
Cyclic AMP Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells
Methods in molecular biology·2022
Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells
Methods in molecular biology·2022
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands
Journal of Medicinal Chemistry·2022· 27 citedOpen Access
Motor-like Tics are Mediated by CB2 Cannabinoid Receptor-dependent and Independent Mechanisms Associated with Age and Sex
Molecular Neurobiology·2022· 6 citedOpen Access
Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2
eLife·2022· 13 citedOpen Access
Author response: Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2
2022Open Access
Synthesis and In Vitro Characterization of Selective Cannabinoid CB2 Receptor Agonists: Biological Evaluation against Neuroblastoma Cancer Cells
Molecules·2022· 10 citedOpen Access
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators
European Journal of Pharmaceutical Sciences·2021· 4 citedOpen Access
Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressure
Bioorganic & Medicinal Chemistry·2021· 11 citedOpen Access
Assessing the treatment of cannabidiolic acid methyl ester: a stable synthetic analogue of cannabidiolic acid on c-Fos and NeuN expression in the hypothalamus of rats
Journal of Cannabis Research·2021· 3 citedOpen Access
CCDC 1861406: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 1861405: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
CCDC 1861417: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
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Frequent Co-authors

Ruth A. Ross(8), Raphael Mechoulam(6), Lesley Stevenson(5), Vincenzo Di Marzo(5), L Hanŭs(4), Gareth Pryce(3), J. Ludovic Croxford(3), Alexandros Makriyannis(3), M. G. Cascio(3), Aviva Breuer(2), Graeme Griffin(2), A­llyn C. Howlett(2), Adèle Thomas(2), Gemma L. Baillie(2), David Baker(2), Peter Brown(2), Lorna Layward(2), Marnie Duncan(2), Sonyuan Lin(2), Heather C Brockie(2)