Hanna Tarhonskaya

AbbVie (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index750citations26works3.02yr avg
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Research Topics

Epigenetics and DNA Methylation(10), Cancer, Hypoxia, and Metabolism(8), Histone Deacetylase Inhibitors Research(8), RNA modifications and cancer(7), Metal-Catalyzed Oxygenation Mechanisms(6)

Publications26 total

A role for the autophagy receptor NBR1 in the degradation of tau aggregates
Neurobiology of Disease·2025· 3 citedOpen Access
The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases
2019Open Access
The Clinically Used Iron Chelator Deferasirox Is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases
ACS Chemical Biology·2019· 30 cited
The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases
2019Open Access
The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases
2019Open Access
The Clinically Used Iron Chelator Deferasirox is an Inhibitor of Epigenetic JumonjiC Domain-Containing Histone Demethylases
2019Open Access
Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal <em>Trichoplax adhaerens</em>
Hypoxia·2018· 24 citedOpen Access
Synthesis and Biological Evaluation of Tripartin, a Putative KDM4 Natural Product Inhibitor, and 1‐Dichloromethylinden‐1‐ol Analogues
ChemMedChem·2018· 15 cited
YcfDRM is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase
Extremophiles·2018· 6 citedOpen Access
In Vitro Enzyme Assays for JmjC‐Domain‐Containing Lysine Histone Demethylases (JmjC‐KDMs)
Current Protocols in Pharmacology·2018· 5 cited
Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens
SHILAP Revista de lepidopterología·2018· 1 citedOpen Access
Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates
Journal of Molecular Biology·2017· 38 citedOpen Access
Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
Molecular Cell·2017· 108 citedOpen Access
Use of ferrous iron by metallo-β-lactamases
Journal of Inorganic Biochemistry·2016· 21 citedOpen Access
Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase
Biochemistry·2015· 24 citedOpen Access
Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor
Journal of Biological Chemistry·2015· 89 citedOpen Access
The crystal structure of viral collagen prolyl hydroxylase vCPH from Paramecium Bursaria Chlorella virus-1 - Truncated Construct
2015
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases
Chemical Communications·2015· 41 citedOpen Access
Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1
Chemical Science·2014· 42 citedOpen Access
Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability
Journal of Antimicrobial Chemotherapy·2014· 61 citedOpen Access
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Frequent Co-authors

Christopher J. Schofield(22), Emily Flashman(14), Akane Kawamura(10), Sarah E. Wilkins(7), Kerstin Lippl(7), Kuo‐Feng Hsu(6), Rebecca L. Hancock(6), Martine I. Abboud(6), Tzu‐Lan Yeh(5), Martin Roatsch(5), Inga Hoffmann(5), Kerstin Serrer(5), Isabelle Moneke(5), Theresa D. Ahrens(5), Dina Robaa(5), Sandra Wenzler(5), Henriette Franz(5), Wolfgang Sippl(5), Silke Laßmann(5), Sven Diederichs(5)