Jennifer A. Young

AbbVie (United States) — United States

Physics and Astronomy · Physical Sciences

31h-index3.0kcitations114works6.02yr avg
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Research Topics

Nuclear Physics and Applications(10), Carcinogens and Genotoxicity Assessment(7), Antibiotic Resistance in Bacteria(6), Ubiquitin and proteasome pathways(6), Synthesis and properties of polymers(6)

Publications114 total

In-Cell Approach to Evaluate E3 Ligases for Use in Targeted Protein Degradation
Journal of the American Chemical Society·2025· 5 citedOpen Access
An in-cell approach to evaluate E3 ligases for use in targeted protein degradation
2024· 1 citedOpen Access
Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex
RSC Medicinal Chemistry·2024· 12 citedOpen Access
Chemical Tools for the Gid4 Subunit of the Human E3 Ligase C-terminal to LisH (CTLH) Degradation Complex
2023· 6 citedOpen Access
Synthesis of PEG-Functionalized Amines Using Ruthenium-Catalyzed Hydrogen Borrowing
Organic Letters·2020· 5 cited
Delineating the role of cooperativity in the design of potent PROTACs for BTK
Proceedings of the National Academy of Sciences·2018· 409 citedOpen Access
MOESM3 of Defining functional diversity for lignocellulose degradation in a microbial community using multi-omics studies
Figshare·2018Open Access
Sphingosine Toxicity in EAE and MS: Evidence for Ceramide Generation via Serine-Palmitoyltransferase Activation
Neurochemical Research·2017· 45 citedOpen Access
Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists
Scientific Reports·2016· 60 citedOpen Access
Intrinsic reactivity profile of electrophilic moieties to guide covalent drug design: N-α-acetyl-<scp>l</scp>-lysine as an amine nucleophile
MedChemComm·2016· 63 cited
Corrigendum to “Novel monobactams utilizing a siderophore uptake mechanism for the treatment of Gram-negative infections” [Bioorg. Med. Chem. Lett. 22/18 (2012) 5989–5994]
Bioorganic & Medicinal Chemistry Letters·2015· 1 cited
Deletion of FADD in Macrophages and Granulocytes Results in RIP3- and MyD88-Dependent Systemic Inflammation
PLoS ONE·2015· 18 citedOpen Access
ChemInform Abstract: One‐Pot Oxidation and Rearrangement of Propargylamines and in situ Pyrazole Synthesis.
ChemInform·2015
One-Pot Oxidation and Rearrangement of Propargylamines and<i>in Situ</i>Pyrazole Synthesis
Organic Letters·2014· 44 cited
Siderophore Receptor-Mediated Uptake of Lactivicin Analogues in Gram-Negative Bacteria
Journal of Medicinal Chemistry·2014· 54 citedOpen Access
Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin–restricted miRNA antagonists of miR-27
Blood·2013· 70 cited
Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity
Journal of Medicinal Chemistry·2013· 63 cited
Commensal Microbiota Are Required for Systemic Inflammation Triggered by Necrotic Dendritic Cells
Cell Reports·2013· 27 citedOpen Access
Consequences of dendritic cell necroptosis on the immune system (P5105)
The Journal of Immunology·2013
Synthetic approaches to mixed ligand chelators on tert-butylphenol–formaldehyde oligomer (PFO) platforms
Tetrahedron·2012· 4 citedOpen Access
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Frequent Co-authors

Jeremy T. Starr(7), Nicolai S. C. van Oers(7), Brandon P. Schuff(5), J.L. Epler(5), Lisa A. Pitcher(5), Mark C. Noe(4), Veerabahu Shanmugasundaram(4), Matthew F. Brown(4), T. Kameswar Rao(4), Michael D. Huband(4), Meredith A. Mathis(4), Daniel P. Uccello(3), William Lijinsky(3), Astar Winoto(3), Alice A. Hardigree(3), Mark E. Flanagan(3), Manjinder S. Lall(3), Jeffrey Casavant(3), Joel R. Hardink(3), Trong-Trieu Hoang(3)