E. J. Tavares da Silva

University of Coimbra — Portugal

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.0kcitations96works6.02yr avg
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Research Topics

Estrogen and related hormone effects(40), Steroid Chemistry and Biochemistry(23), Bioactive Compounds and Antitumor Agents(15), Inflammatory mediators and NSAID effects(11), Crystal structures of chemical compounds(10)

Publications96 total

Cutting-edge design approaches for steroidal aromatase inhibitors: new horizons for hormone-dependent cancer
Expert Opinion on Drug Discovery·2025
Steroidal derivatives in pancreatic cancer: Paving the way to new anticancer drugs
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer·2025
Novel steroidal oximes as antiproliferative agents: Design, synthesis and biological activity evaluation
Bioorganic Chemistry·2025· 1 citedOpen Access
New Promising Steroidal Aromatase Inhibitors with Multi-Target Action on Estrogen and Androgen Receptors for Breast Cancer Treatment
Cancers·2025· 6 citedOpen Access
Glioblastoma: Characterization, Current Therapy and Future Prospects
SSRN Electronic Journal·2025Open Access
Plant-derived and dietary phenolic cinnamic acid derivatives: Anti-inflammatory properties
Food Chemistry·2024· 37 citedOpen Access
Steroidal epoxides as anticancer agents in lung, prostate and breast cancers: The case of 1,2-epoxysteroids
Biochemical Pharmacology·2024· 4 cited
Novel Steroidal Oximes as Potential Anticancer Agents: Design, Synthesis and Biological Activity Evaluation
SSRN Electronic Journal·2024Open Access
Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review
Bioorganic Chemistry·2023· 74 citedOpen Access
The Structural Diversity and Biological Activity of Steroid Oximes
Molecules·2023· 11 citedOpen Access
An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromatase Inhibitor for Estrogen Receptor-Positive (ER+) Breast Cancer: Effects on Sensitive and Resistant Cell Lines
Molecules·2023· 13 citedOpen Access
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids
Bioorganic Chemistry·2022· 12 citedOpen Access
Promising benefits of cold atmospheric plasma-based therapies against bladder cancer
European Urology Open Science·2021Open Access
Design, synthesis, and antitumor activity evaluation of steroidal oximes
Bioorganic & Medicinal Chemistry·2021· 18 cited
Oxymestane, a cytostatic steroid derivative of exemestane with greater antitumor activity in non-estrogen-dependent cell lines
The Journal of Steroid Biochemistry and Molecular Biology·2021· 6 cited
The Role of Ga-68-PSMA PET/CT in the Initial Staging of Prostate Cancer – A Single Center 4 Year Experience
SHILAP Revista de lepidopterología·2021Open Access
Contributors
Elsevier eBooks·2021
The health components of spices and herbs: The medicinal chemistry point of view
Elsevier eBooks·2021· 4 cited
Synthesis and Characterization of a Novel Nanomicellar System Pluronic-PEI Suitable for Gene and Drug Co-Delivery in Cancer Therapy
2020· 1 citedOpen Access
Development and Characterization of a Novel Mixed Polymeric Micelle as a Potential Therapeutic Strategy for Osteosarcoma
2020· 2 citedOpen Access
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Frequent Co-authors

Fernanda M.F. Roleira(45), Carla Varela(31), Georgina Correia‐da‐Silva(22), Natércia Teixeira(22), Saúl C. Costa(18), Cristina Amaral(17), Rui A. Carvalho(11), Ana R. Gomes(7), Ana Salomé Pires(6), Fernanda Borges(5), M. L. Sá e Melo(5), M. J. M. de Almeida(5), L. C. R. Andrade(5), Jorge Garrido(4), Margarida Cepa(4), Stefano Alcaro(4), Giosuè Costa(4), Ana Cristina Gonçalves(4), Ana Margarida Abrantes(4), Maria Filomena Botelho(4)