Cristina Mayor‐Ruiz

Institute for Research in Biomedicine — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index1.4kcitations30works2.42yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protein Degradation and Inhibitors(14), Ubiquitin and proteasome pathways(12), CRISPR and Genetic Engineering(7), Histone Deacetylase Inhibitors Research(5), Click Chemistry and Applications(4)

Publications30 total

Opportunities in proximity modulation: Bridging academia and industry
Molecular Cell·2025· 2 citedOpen Access
Mutations that stick: Unexpected discovery of molecular glue mimicry
Molecular Cell·2025
Thoughts for the future
Nature Chemical Biology·2024· 1 cited
Targeted KRAS <sup>G12V</sup> degradation elicits efficient and durable lung adenocarcinoma regression <i>in vivo</i>
2024Open Access
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP
Nature Chemical Biology·2024· 17 citedOpen Access
Graphical Abstract: Angew. Chem. Int. Ed. 12/2024
Angewandte Chemie International Edition·2024Open Access
Graphisches Inhaltsverzeichnis: Angew. Chem. 12/2024
Angewandte Chemie·2024Open Access
Innentitelbild: Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders (Angew. Chem. 12/2024)
Angewandte Chemie·2024Open Access
Inside Cover: Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders (Angew. Chem. Int. Ed. 12/2024)
Angewandte Chemie International Edition·2024Open Access
Chemical rewiring of ubiquitination by degraders and their selectivity routes
Nature Structural & Molecular Biology·2024· 4 cited
Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders
Angewandte Chemie·2023· 2 cited
Discovery and Mechanistic Elucidation of NQO1‐Bioactivatable Small Molecules That Overcome Resistance to Degraders
Angewandte Chemie International Edition·2023· 2 cited
Proximity-inducing pharmacology
Nature Chemical Biology·2023· 1 cited
Design principles for cyclin K molecular glue degraders
Nature Chemical Biology·2023· 82 citedOpen Access
Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway
Nature Communications·2023· 13 citedOpen Access
Biophysical and Computational Approaches to Study Ternary Complexes: A ‘Cooperative Relationship’ to Rationalize Targeted Protein Degradation
ChemBioChem·2023· 41 citedOpen Access
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting the oxysterol-binding protein OSBP
2023· 1 citedOpen Access
Molecular Glue Degraders: From Serendipity to Hunting and Design
2022· 6 cited
Chasing molecular glue degraders: screening approaches
Chemical Society Reviews·2022· 158 citedOpen Access
Identification and selectivity profiling of small-molecule degraders via multi-omics approaches
Cell chemical biology·2021· 43 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Georg E. Winter(13), Marko Cigler(9), Carles Perez‐Lopez(7), Óscar Fernández-Capetillo(6), Joan Pous(6), Bárbara M. G. Barbosa(5), Aikaterini Sfyaki(5), Sergi Rafael(5), Ferran José‐Duran(5), Carolina Sánchez(5), Marta Vilaseca(5), Antoni Riéra(5), Hana Imrichová(4), Nicolas H. Thomä(4), Sergio Ruiz(4), Sagrario Ortega(4), Mar Vilanova(4), Marina Gay(4), Sophie Bauer(3), Matthias Brand(3)