Mariko Kambe

Tohoku Medical Megabank Organization — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index539citations39works1.32yr avg
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Research Topics

Glycosylation and Glycoproteins Research(9), Cell Adhesion Molecules Research(7), Immunotherapy and Immune Responses(5), Microbial Inactivation Methods(4), Caveolin-1 and cellular processes(4)

Publications36 total

Cohort Profile Update: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study) 2023 update
International Journal of Epidemiology·2025Open Access
Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins
International Journal of Molecular Sciences·2024· 3 citedOpen Access
Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells.
PubMed·2024· 1 citedOpen Access
Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas
Scientific Reports·2023· 17 citedOpen Access
Functional validation of novel variants in <scp><i>B4GALNT1</i></scp> associated with early‐onset complex hereditary spastic paraplegia with impaired ganglioside synthesis
American Journal of Medical Genetics Part A·2022· 11 citedOpen Access
Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins
International Journal of Molecular Sciences·2021· 34 citedOpen Access
TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes
Scientific Reports·2019· 6 citedOpen Access
Differential roles of gangliosides in malignant properties of melanomas
PLoS ONE·2018· 58 citedOpen Access
Control of cell dynamics by tumor associated glycosphingolipids: time-lapse analysis with fluorescence-labeled glycosphingolipids
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2017
Inflammatory Reactions in Microenvironments, Leading to Melanomagenesis
Journal of Clinical & Cellular Immunology·2017· 1 cited
Randomized Phase II Trial Comparing Carboplatin Plus Weekly Paclitaxel and Docetaxel Alone in Elderly Patients With Advanced Non-Small Cell Lung Cancer: North Japan Lung Cancer Group Trial 0801
The Oncologist·2014· 20 citedOpen Access
UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6
Biochemical and Biophysical Research Communications·2014· 20 cited
Ganglioside <scp>GD</scp>3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas
Cancer Science·2013· 29 citedOpen Access
Phase II trial of cetuximab (Cmab) plus irinotecan (CPT-11) for chemorefractory Japanese patients with advanced and/or metastatic colorectal cancer (mCRC), to evaluate the efficacy and safety based on <i>KRAS</i>, <i>BRAF</i>, <i>PIK3CA</i>, <i>NRAS</i>, and <i>AKT1</i> mutation status (T-CORE0801).
Journal of Clinical Oncology·2013
Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides
Cancer Science·2011· 33 citedOpen Access
Phase I study of irinotecan by 24-h intravenous infusion in combination with 5-fluorouracil in metastatic colorectal cancer
International Journal of Clinical Oncology·2011· 3 cited
Formation of acrylamide from glucans and asparagine
New Biotechnology·2011· 4 cited
Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains
Journal of Biological Chemistry·2010· 112 citedOpen Access
Phase II Trial of S-1 plus Low-Dose Cisplatin for Unresectable and Recurrent Gastric Cancer (JFMC27-9902 Step2)
Oncology·2010· 5 cited
Experimental application of Holmium:yttrium-aluminum-garnet laser-induced shock wave as a drug delivery system
The Journal of the Acoustical Society of America·2006· 2 cited
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Frequent Co-authors

Koichi Furukawa(12), Orie Tajima(11), Keiko Furukawa(11), Yuhsuke Ohmi(9), Yuki Ohkawa(7), Maiko Miyata(6), Ryunosuke Kanamaru(6), Robiul Hasan Bhuiyan(6), Rika Takeuchi(4), Daisaku Arita(4), Farhana Yesmin(4), Kei Kaneko(4), Tadao Funato(4), Makio Gamo(4), Yasuko Murakawa(4), Yasushi Mitachi(4), Kazunori Hamamura(3), Naomasa Ioritani(3), Seiichi Orikasa(3), Rihito Kanamaru(3)