Orie Tajima

Chubu University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index1.4kcitations56works3.02yr avg
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Research Topics

Glycosylation and Glycoproteins Research(43), Sphingolipid Metabolism and Signaling(12), Cell Adhesion Molecules Research(7), Galectins and Cancer Biology(7), ATP Synthase and ATPases Research(6)

Publications56 total

GD2 is a Crucial Ganglioside in the Signal Modulation and Application as a Target of Cancer Therapeutics
Cancer Science·2025· 5 citedOpen Access
Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins
International Journal of Molecular Sciences·2024· 3 citedOpen Access
Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells.
PubMed·2024· 1 citedOpen Access
Disordered testosterone transport in mice lacking the ganglioside <scp>GM2</scp>/<scp>GD2</scp> synthase gene
FEBS Open Bio·2023· 2 citedOpen Access
Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas
Scientific Reports·2023· 17 citedOpen Access
Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway
PLoS ONE·2023· 6 citedOpen Access
Opposite Functions of Mono- and Disialylated Glycosphingo-Lipids on the Membrane of Cancer Cells
2023
Signaling domains of cancer-associated glycolipids
Glycoconjugate Journal·2022· 13 cited
Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins
International Journal of Molecular Sciences·2021· 34 citedOpen Access
Molecular mechanisms for the reduction of hepatic fat accumulation via insulin signaling in glycosphingolipid deficient mice
The Japanese Biochemical Society·2020
Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia
The Journal of Biochemistry·2020· 5 cited
Novel Molecular Mechanisms of Gangliosides in the Nervous System Elucidated by Genetic Engineering
International Journal of Molecular Sciences·2020· 19 citedOpen Access
Integrative Roles of Gangliosides in the Nervous System: Novel Molecular Mechanisms Elucidated by Genetic Engineering
2020
TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes
Scientific Reports·2019· 6 citedOpen Access
New era of research on cancer‐associated glycosphingolipids
Cancer Science·2019· 99 citedOpen Access
Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration — Great progress over the last 70 years —
Proceedings of the Japan Academy Series B·2019· 9 citedOpen Access
Technologies to Elucidate Functions of Glycans
2019
Differential roles of gangliosides in malignant properties of melanomas
PLoS ONE·2018· 58 citedOpen Access
Molecular mechanisms for the reduction of hepatic fat accumulation in glycosphingolipid deficient mice
The Japanese Biochemical Society·2018
Gangliosides in Inflammation and Neurodegeneration
Progress in molecular biology and translational science·2018· 20 cited
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Frequent Co-authors

Koichi Furukawa(47), Keiko Furukawa(37), Yuhsuke Ohmi(31), Yuki Ohkawa(29), Robiul Hasan Bhuiyan(12), Yuji Kondo(12), Mariko Kambe(11), Noboru Hashimoto(11), Farhana Yesmin(8), Kazunori Hamamura(7), Yasuo Sugiura(7), Kei Kaneko(7), Noriyo Tokuda(6), Yoshio Yamauchi(6), Maiko Miyata(5), Pu Zhang(5), Keiko Furukawa(5), Takeshi Urano(4), Koichi Honke(4), Michio Ohta(3)