Christiano Tanese de Souza

Ottawa Hospital — Canada

Medicine · Health Sciences

18h-index1.9kcitations85works2.62yr avg
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Research Topics

Cancer, Stress, Anesthesia, and Immune Response(28), Immune Cell Function and Interaction(22), Virus-based gene therapy research(18), CAR-T cell therapy research(17), Viral Infections and Vectors(15)

Publications84 total

Oncolytic vaccinia virus encoding constitutively active EPAC remodels the tumor microenvironment to enhance therapeutic efficacy with chemotherapy and surgery
Journal for ImmunoTherapy of Cancer·2026Open Access
Preventing surgery-induced natural killer cell suppression and metastases by inhibiting PI3K-gamma signaling in myeloid-derived suppressor cells
Journal for ImmunoTherapy of Cancer·2026Open Access
LAG3 Marks Activated but Hyporesponsive NK Cells
European Journal of Immunology·2025· 2 citedOpen Access
Characterizing postoperative T and B cell dysfunction in cancer surgery patients, using COVID-19 as a model antigen
International Journal of Surgery·2025Open Access
Characterizing postoperative T and B cell dysfunction in cancer surgery patients, using COVID-19 as a model antigen
2024
LAG3 marks activated but hyporesponsive NK cells
2024Open Access
Preventing surgery induced immune suppression and metastases by inhibiting PI3K-gamma signalling in Myeloid-Derived Suppressor Cells
2024
Complementary dual-virus strategy drives synthetic target and cognate T-cell engager expression for endogenous-antigen agnostic immunotherapy
Nature Communications·2024· 12 citedOpen Access
PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway
The Journal of Experimental Medicine·2024· 9 citedOpen Access
Supplementary Fig. S.6 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.2 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.1 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.2 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.7 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.4 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.7 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.5 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary figure legends from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Supplementary Fig. S.6 from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
Data from NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
2023Open Access
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Frequent Co-authors

Rebecca C. Auer(42), John C. Bell(28), Lee‐Hwa Tai(26), Almohanad A. Alkayyal(20), Jiqing Zhang(18), Abhirami A. Ananth(15), Andrew P. Makrigiannis(13), Shalini Sahi(13), David F. Stojdl(12), Michael A. Kennedy(12), Carolina S. Ilkow(9), Charles Lefebvre(9), Ahmad Bakur Mahmoud(9), Theresa Falls(8), Leonard Angka(8), Brian D. Lichty(7), Greg O. Cron(7), Blair Macdonald(7), Jean‐Simon Diallo(6), E. Celia Marginean(6)