Jian Payandeh

Exelixis (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index7.8kcitations102works5.52yr avg
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Research Topics

Ion channel regulation and function(35), Monoclonal and Polyclonal Antibodies Research(14), Nicotinic Acetylcholine Receptors Study(12), Bacterial Genetics and Biotechnology(11), RNA and protein synthesis mechanisms(9)

Publications102 total

The discovery and structural basis of two distinct state-dependent inhibitors of BamA
Nature Communications·2024· 16 citedOpen Access
William A. Catterall (1946–2024)
Neuron·2024Open Access
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation
Journal of Medicinal Chemistry·2024· 3 citedOpen Access
Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability
mAbs·2024· 3 citedOpen Access
Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8
Nature Communications·2023· 24 citedOpen Access
Data from Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
2023Open Access
Supplementary Data from Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
2023Open Access
Data from Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
2023Open Access
Supplementary Data from Anti-LYPD1/CD3 T-Cell-Dependent Bispecific Antibody for the Treatment of Ovarian Cancer
2023Open Access
Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
eLife·2023· 22 citedOpen Access
Author response: Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
2023Open Access
CryoEM reveals unprecedented binding site for Na <sub>V</sub> 1.7 inhibitors enabling rational design of potent hybrid inhibitors
2022Open Access
Structure of the core human NADPH oxidase NOX2
Nature Communications·2022· 92 citedOpen Access
Cell-based receptor discovery identifies host factors specifically targeted by the SARS CoV-2 spike
Communications Biology·2022· 5 citedOpen Access
Novel Antibody Interfaces Revealed Through Structural Mining
2022Open Access
Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel
Nature Communications·2022· 24 citedOpen Access
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization
Science Advances·2022· 30 citedOpen Access
Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity
Journal of Medicinal Chemistry·2022· 28 cited
Corrigendum to “A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants” [Bioorg. Chem. 116 (2021) 105376]
Bioorganic Chemistry·2022
Structure and function of the human NALCN-UNC79-UNC80-FAM155A-CaM complex
Biophysical Journal·2022
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Frequent Co-authors

Christopher P. Arthur(14), Claudio Ciferri(13), Christopher M. Koth(12), David H. Hackos(10), Alexis Rohou(10), Hoangdung Ho(9), Christine Tam(8), Tianbo Li(7), Alberto Estevez(6), James T. Koerber(6), E.F. Pai(6), Marc Kschonsak(6), Ning Zheng(5), William A. Catterall(5), Yvonne Franke(5), Cary D. Austin(5), Lionel Rougé(5), Nancy Chiang(5), Christine Kugel(5), Gerald Nakamura(5)