Robert E. MacLaren

National Health Service — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

67h-index18.4kcitations647works4.72yr avg
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Research Topics

Retinal Development and Disorders(390), Retinal Diseases and Treatments(225), Retinal and Optic Conditions(83), CRISPR and Genetic Engineering(77), Virus-based gene therapy research(76)

Publications635 total

Cataract surgery with autosomal recessive cornea plana caused by a novel KERA mutation
American Journal of Ophthalmology Case Reports·2026Open Access
Phenotypic Manifestations in Female Carriers of <i>RPGR</i> ORF15 Variants Causing X-Linked Cone Dystrophy
JAMA Ophthalmology·2026Open Access
IMPG2-associated retinal dystrophy with a novel missense variant and therapeutic options via adenine base editing
Ophthalmic Genetics·2026Open Access
Expanding the Genetic Spectrum in IMPG1 and IMPG2 Retinopathy
Genes·2025Open Access
The Clinical Pharmacist as Principal Investigator—2026
JACCP JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY·2025Open Access
Central Retinal Sensitivity Decline in RPGR-Related Retinal Phenotypes
American Journal of Ophthalmology·2025Open Access
Investigating ethnicity-related variability in the human L-cone spectral sensitivity function
2025Open Access
#CC-Paper-01 Clinical and electrophysiological profile in a female carrier of the c.3308_3309delAT (p.Tyr1103Serfs*7)<i>RPGR</i>variant associated with X-linked cone dystrophy
2025Open Access
Gene Therapy Strategies for the Treatment of Bestrophinopathies
International Journal of Molecular Sciences·2025· 1 citedOpen Access
Multimodal imaging and electrophysiological features in bradyopsia associated with homozygous variants (c.895T&gt;C) in Regulator of G-protein Signaling 9 ( <i>RGS9</i> )
Ophthalmic Genetics·2025
DIRECT POSTERIOR RETINAL INJURY CAUSED BY INTRAVITREAL INJECTIONS
Retina·2025
Genotype–Phenotype Correlations in PRPH2 Retinopathies: A Comprehensive Analysis of 36 Patients from the Oxford Eye Hospital, UK
Genes·2025Open Access
Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates
2025Open Access
An Analysis of Scotopic Microperimetry in Healthy Adults
Translational Vision Science & Technology·2025Open Access
Characterizing Inner Retinal Changes in End-Stage Inherited Retinal Diseases That Might be Suitable for Optogenetic Therapies
Translational Vision Science & Technology·2025· 1 citedOpen Access
Exploring standard and low luminance visual acuity and the Moorfields Acuity Chart as outcome measures in inherited retinal disease
Ophthalmic and Physiological Optics·2025· 1 citedOpen Access
Functional vision tests as clinical trial outcome measures in ophthalmology: a scoping review
BMJ Open·2025· 2 citedOpen Access
Approval of retinal gene therapies in the US and Europe based on visual acuity and microperimetry
Expert Review of Ophthalmology·2025Open Access
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy
Progress in Retinal and Eye Research·2025· 12 citedOpen Access
CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system
Gene Therapy·2025· 2 citedOpen Access
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Frequent Co-authors

Alun R. Barnard(15), Robin R. Ali(10), Kanmin Xue(9), Markus Groppe(8), Mandeep S. Singh(8), Thomas L. Edwards(8), R. A. Pearson(7), Susan M. Downes(7), Jane C. Sowden(6), Miguel C. Seabra(6), Michelle E. McClements(6), Jasleen K. Jolly(6), Charles L. Cottriall(5), Tanya Tolmachova(5), Yanaí Durán(5), Graeme C. Black(4), Andrew Lotery(4), Andrew R. Webster(4), Alexander J. Smith(4), Eberhart Zrenner(4)