Colby R. Sandate

Friedrich Miescher Institute — Switzerland

Neuroscience · Life Sciences

8h-index783citations27works2.02yr avg
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Research Topics

Circadian rhythm and melatonin(11), Light effects on plants(8), Photosynthetic Processes and Mechanisms(4), Atomic and Subatomic Physics Research(4), Cancer, Hypoxia, and Metabolism(3)

Publications27 total

Nucleosomes specify co-factor access to p53
Molecular Cell·2025· 2 citedOpen Access
BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma
Nature Communications·2025· 5 citedOpen Access
BMAL1-HIF2α heterodimers contribute to ccRCC
2024Open Access
BMAL1-HIF2α heterodimers contribute to ccRCC
2024· 1 citedOpen Access
Structural insights into viral hijacking of p53 by E6 and E6AP
2023· 4 citedOpen Access
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability
Molecular Cell·2023· 66 citedOpen Access
Coupling of distant ATPase domains in the circadian clock protein KaiC
Nature Structural & Molecular Biology·2022· 20 citedOpen Access
Closing the negative feedback loop: a tandem ATPase keeps circadian time by coupling distant enzymatic activities
Biophysical Journal·2022
A C2-symmetric state in the AAA+ KaiC hexamer coordinates structural and functional modes within a molecular clock
Biophysical Journal·2022
Hidden conformations differentiate day and night in a circadian pacemaker
2021· 3 citedOpen Access
Extended conformation of daytime state KaiC
2021
Extended conformation of nighttime state KaiC
2021
Compressed conformation of nighttime state KaiC
2021
How CRY regulates the clock: structural studies of a dynamic mammalian circadian complex
Acta Crystallographica Section A Foundations and Advances·2020Open Access
Author Correction: An allosteric network in spastin couples multiple activities required for microtubule severing
Nature Structural & Molecular Biology·2020· 3 citedOpen Access
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing
eLife·2020· 73 citedOpen Access
Author response: Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing
2020· 1 citedOpen Access
Frozen in Time - How Phosphorylation Induces Conformational Rearrangement in the Circadian AAA+ ATPase KaiC
Biophysical Journal·2020Open Access
The molecular principles governing the activity and functional diversity of AAA+ proteins
Nature Reviews Molecular Cell Biology·2019· 266 citedOpen Access
Protein dynamics regulate distinct biochemical properties of cryptochromes in mammalian circadian rhythms
2019· 2 citedOpen Access
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Frequent Co-authors

Gabriel C. Lander(16), Carrie L. Partch(14), Jeffrey A. Swan(8), Nicolas H. Thomä(6), Alicia K. Michael(5), Jennifer L. Fribourgh(5), Sarvind Tripathi(5), Katja Lamia(4), Ashutosh Srivastava(4), Tsuyoshi Hirota(4), Florence Tama(4), Archana G. Chavan(4), Alfred M. Freeberg(4), Diana Etwaru(4), Dustin C. Ernst(4), Joseph G. Palacios(4), Susan S. Golden(4), Andy LiWang(4), Peter Hsu(3), Christin Rakers(3)