Kazuo Takayama

Tokyo Medical and Dental University — Japan

Medicine · Health Sciences

47h-index7.3kcitations299works10.22yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(73), Pluripotent Stem Cells Research(47), CRISPR and Genetic Engineering(36), 3D Printing in Biomedical Research(26), Animal Virus Infections Studies(26)

Publications298 total

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity
Nature Communications·2025Open Access
Mpox virus OPG175 negatively regulates viral replication by controlling Wnt signaling
iScience·2025Open Access
Mpox virus replicates in lung organoids without significantly affecting their cellular function
Biochemistry and Biophysics Reports·2025Open Access
Genome edited intestine liver on a chip system for integrated intestinal hepatic drug absorption and metabolism evaluation
Scientific Reports·2025· 1 citedOpen Access
A cattle-derived human H5N1 isolate suppresses innate immunity despite efficient replication in human respiratory organoids
2025Open Access
Evolution of BA.2.86 to JN.1 reveals that functional changes in non-structural viral proteins are required for fitness of SARS-CoV-2
Journal of Virology·2025· 5 citedOpen Access
Multifunctional materials with potential antiviral applications in face masks, face shields, and hydrogels against mpox virus
Scientific Reports·2025Open Access
The role of IL-4+ memory T cells in SARS-CoV-2 booster vaccination
International Immunology·2025
Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human cortical organoid microphysiological systems
Science Advances·2025· 1 citedOpen Access
Monoclonal antibodies against human TMPRSS2 prevent infection by any SARS-CoV-2 variant
iScience·2025Open Access
Changes in ORF4 of HCoV-229E under different culture conditions
Journal of General Virology·2025· 1 citedOpen Access
Evolutionary dynamics of heparan sulfate utilization by SARS-CoV-2
mBio·2025Open Access
Considerations for developing CYP induction assays in hepatocytes: Insights from a multilaboratory study
European Journal of Cell Biology·2025· 1 citedOpen Access
SARS-CoV-2 Nsp1-Resistant Modified RNA for the Creation of Nsp1-Responsive Systems
ACS Synthetic Biology·2025
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity
2025· 2 citedOpen Access
Advancing intestinal disease research using gut-on-a-chip
Regenerative Therapy·2025· 1 citedOpen Access
Human iPS cell–derived respiratory organoids as a model for respiratory syncytial virus infection
Life Science Alliance·2025· 6 citedOpen Access
Hypertonic intranasal vaccines gain nasal epithelia access to exert strong immunogenicity
Mucosal Immunology·2025· 2 cited
Future direction of animal alternative/microphysiological systems in drug discovery and development
Drug Metabolism and Pharmacokinetics·2025
Understanding monocyte-driven neuroinflammation in Alzheimer’s disease using human brain organoid microphysiological systems
2025· 2 citedOpen Access
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Frequent Co-authors

Hiroyuki Mizuguchi(22), Fuminori Sakurai(20), Kenji Kawabata(11), Sayaka Deguchi(10), Akatsuki Saito(10), Masashi Tachibana(10), Rina Hashimoto(9), Yasuhito Nagamoto(9), Tomokazu Tamura(8), Jumpei Ito(8), Keiya Uriu(8), Hesham Nasser(8), Naganori Nao(8), Rigel Suzuki(8), Masumi Tsuda(8), Yusuke Kosugi(8), Takasuke Fukuhara(8), Shinya Tanaka(8), Keita Matsuno(8), Kei Sato(8)