Edward Bertaccini

VA Palo Alto Health Care System — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.0kcitations112works0.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Receptor Mechanisms and Signaling(38), Nicotinic Acetylcholine Receptors Study(32), Anesthesia and Sedative Agents(28), Neuroscience and Neuropharmacology Research(22), Anesthesia and Neurotoxicity Research(22)

Publications112 total

Putative RNA editing of a nicotinic receptor increases acetylcholine sensitivity
The Journal of General Physiology·2026
Assessment of a new class of slow γ-aminobutyric acid type A receptor anesthetic on mouse neuronal and astrocyte mitochondrial function
2025Open Access
Comparative Electroencephalographic Profile of a New Anesthetic and Anticonvulsant That Is Selective for the GABAAR Slow Receptor Subtype
Anesthesia & Analgesia·2024· 1 citedOpen Access
Anesthesia, Coming of Age in the World of Modern In Silico Drug Design
Anesthesiology·2023· 4 cited
Modulation of α1β3γ2 GABA <sub>A</sub> receptors expressed in <i>X. laevis</i> oocytes using a propofol photoswitch tethered to the transmembrane helix
Proceedings of the National Academy of Sciences·2021· 8 citedOpen Access
A newly developed anesthetic based on a unique chemical core
Proceedings of the National Academy of Sciences·2019· 17 citedOpen Access
An In Vitro Model for Identifying Cardiac Side Effects of Anesthetics
Anesthesia & Analgesia·2018· 13 citedOpen Access
Insights Into Receptor-Based Anesthetic Pharmacophores and Anesthetic–Protein Interactions
Methods in enzymology on CD-ROM/Methods in enzymology·2018· 5 cited
The Role of the Hydroxyl Group in Propofol–Protein Target Recognition: Insights from ONIOM Studies
The Journal of Physical Chemistry B·2017· 18 cited
Faculty Opinions recommendation of Synthesis and pharmacological evaluation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as potential GABAA-R ligands.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
The Role of the Hydroxyl Group in Propofol–Protein Target Recognition: Insights from ONIOM Studies B
The Journal of Physical Chemistry·2017
Faculty Opinions recommendation of Emerging Molecular Mechanisms of Signal Transduction in Pentameric Ligand-Gated Ion Channels.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2016
Principal Components from Ligand-Gated Ion Channel Structures Enable Ensemble Studies of Microsecond-Scale Transitions
Biophysical Journal·2016Open Access
Identification of an Inhibitory Alcohol Binding Site in GABAaRho1
Biophysical Journal·2016Open Access
General anesthetics interaction with pentameric ligand-gated ion channel GLIC: Insights from ONIOM calculations
2015
Identification of an Inhibitory Alcohol Binding Site in GABA<sub>A</sub>ρ1 Receptors
ACS Chemical Neuroscience·2015· 13 cited
Faculty Opinions recommendation of Structural comparisons of ligand-gated ion channels in open, closed, and desensitized states identify a novel propofol-binding site on mammalian γ-aminobutyric acid type A receptors.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2015
Design and Implementation of a Perioperative Surgical Home at a Veterans Affairs Hospital
Seminars in Cardiothoracic and Vascular Anesthesia·2015· 29 cited
Insights into the Nature of Anesthetic–Protein Interactions: An ONIOM Study
The Journal of Physical Chemistry B·2015· 9 cited
Invasive Mechanical Ventilation in California Over 2000-2009: Implications for Emergency Medicine
Western Journal of Emergency Medicine·2015· 7 citedOpen Access
page 1 of 6Next →

Frequent Co-authors

James R. Trudell(30), Erik Lindahl(10), R. Adron Harris(4), Steven L. Shafer(4), Eran Geller(4), Daryl L. Davies(4), M. Frances Davies(3), Ronald L. Alkana(3), Nicholas P. Franks(3), M Bruce MacIver(3), Juli Barr(3), Andrew Jenkins(2), Neil L. Harrison(2), Juliana Barr(2), Katayoun Zomorodi(2), Thomas Bouillon(2), Samuel Murail(2), Björn Wallner(2), Daniel K. Crawford(2), Özge Yoluk(2)