Paul Kijek

Therapeutics Systems Research Laboratories (United States) — United States

Immunology and Microbiology · Life Sciences

7h-index366citations10works0.02yr avg
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Research Topics

HIV Research and Treatment(3), Cytomegalovirus and herpesvirus research(3), HIV/AIDS drug development and treatment(2), Virus-based gene therapy research(2), Biochemical and Molecular Research(2)

Publications10 total

Synthesis, transport and antiviral activity of Ala–Ser and Val–Ser prodrugs of cidofovir
Bioorganic & Medicinal Chemistry Letters·2011· 14 citedOpen Access
5′-O-D-Valyl<i>ara</i>A, A Potential Prodrug for Improving Oral Bioavailability of the Antiviral Agent Vidarabine
Nucleosides Nucleotides & Nucleic Acids·2009· 15 citedOpen Access
Serine Peptide Phosphoester Prodrugs of Cyclic Cidofovir: Synthesis, Transport, and Antiviral Activity
Molecular Pharmaceutics·2008· 37 citedOpen Access
Serine Side-Chain-linked Peptidomimetic Prodrugs of Cidofovir and Cyclic Cidofovir: C-Ester Effects on Transport and Activation
Antiviral Research·2008· 4 cited
Pharmacokinetics of the CYP 3A Substrate Simvastatin following Administration of Delayed Versus Immediate Release Oral Dosage Forms
Pharmaceutical Research·2008· 83 cited
Novel Synthetic Approaches to Cidofovir and Foscarnet Prodrugs
Antiviral Research·2007· 4 cited
Synthesis and Structure–Activity Aspects of Some Cyclic Cidofovir Peptidomimetic Prodrugs
Antiviral Research·2007· 4 cited
Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir
Bioorganic & Medicinal Chemistry Letters·2006· 17 citedOpen Access
Bile Acid−Oligopeptide Conjugates Interact with DNA and Facilitate Transfection
Molecular Pharmaceutics·2006· 31 citedOpen Access
The Suitability of an in Situ Perfusion Model for Permeability Determinations:  Utility for BCS Class I Biowaiver Requests
Molecular Pharmaceutics·2006· 157 cited

Frequent Co-authors

John M. Hilfinger(8), Stefanie Mitchell(6), B. A. Kashemirov(6), Larryn W. Peterson(5), John C. Drach(5), Charles E. McKenna(5), Katherine Z. Borysko(4), Ulrika Eriksson(3), Julie M. Breitenbach(3), Jae‐Seung Kim(3), Yasuhiro Tsume(2), Gordon L. Amidon(2), Jae Seung Kim(2), Phillip E. Kish(2), J KIM(2), J M Hilfinger(2), Jae-Seung Kim(1), Marija Tubić-Grozdanis(1), Petra Staubach(1), Peter Langguth(1)