Ilse Sienaert

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index1.5kcitations42works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(25), Cellular transport and secretion(12), Calcium signaling and nucleotide metabolism(11), Ion channel regulation and function(9), Receptor Mechanisms and Signaling(7)

Publications42 total

Synthesis and in vitro evaluation of 2-amino-4-N-piperazinyl-6-(3,4-dimethoxyphenyl)-pteridines as dual immunosuppressive and anti-inflammatory agents
Bioorganic & Medicinal Chemistry Letters·2010· 25 cited
Immunosuppressive activity of a new pteridine derivative (4AZA1378) alleviates severity of TNBS-induced colitis in mice
Clinical Immunology·2006· 16 cited
Anti-inflammatory Activity of a Pteridine Derivative (4AZA2096) Alleviates TNBS-Induced Colitis in Mice
Journal of Interferon & Cytokine Research·2006· 12 cited
Dual immune suppressive activity of 4AZA1378 alleviates TNBS-induced colitis in mice
Clinical Immunology·2005
A Novel Ca2+-induced Ca2+ Release Mechanism in A7r5 Cells Regulated by Calmodulin-like Proteins
Journal of Biological Chemistry·2003· 18 citedOpen Access
Pharmacology of inositol trisphosphate receptors
Pflügers Archiv - European Journal of Physiology·2003· 41 cited
A novel Ca2+-induced Ca2+ release mechanism in A7r5 cells regulated by calmodulin-like proteins
Biophysical Journal·2003
The role of calmodulin for inositol 1,4,5-trisphosphate receptor function
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics·2002· 57 cited
Inhibition of IP3R-1, by KN-93 depends on availability of a calmodulin-binding site and IP3R-1 conformation
Molecular Biology of the Cell·2002
Inhibition of the Inositol Trisphosphate Receptor of Mouse Eggs and A7r5 Cells by KN-93 via a Mechanism Unrelated to Ca2+/Calmodulin-dependent Protein Kinase II Antagonism
Journal of Biological Chemistry·2002· 34 citedOpen Access
Localization and function of a calmodulin–apocalmodulin-binding domain in the N-terminal part of the type 1 inositol 1,4,5-trisphosphate receptor
Biochemical Journal·2002· 76 citedOpen Access
Mapping of the ATP-binding Sites on Inositol 1,4,5-Trisphosphate Receptor Type 1 and Type 3 Homotetramers by Controlled Proteolysis and Photoaffinity Labeling
Journal of Biological Chemistry·2001· 50 citedOpen Access
Basic properties of an inositol 1,4,5‐trisphosphate‐gated channel in carp olfactory cilia
European Journal of Neuroscience·2000· 15 cited
Ca2+-calmodulin inhibits Ca2+ release mediated by type-1, -2 and -3 inositol trisphosphate receptors
Biochemical Journal·2000· 27 cited
Ca2+-calmodulin inhibits Ca2+ release mediated by type-1, -2 and -3 inositol trisphosphate receptors
Biochemical Journal·2000· 85 citedOpen Access
Regulation of Inositol 1,4,5-Trisphosphate-Induced Ca2+ Release by Ca2+
2000· 27 cited
Modulation of Inositol 1,4,5-Trisphosphate Binding to the Recombinant Ligand-binding Site of the Type-1 Inositol 1,4,5-Trisphosphate Receptor by Ca2+ and Calmodulin
Journal of Biological Chemistry·1999· 68 citedOpen Access
Adenine-nucleotide binding sites on the inositol 1,4,5-trisphosphate receptor bind caffeine, but not adenophostin A or cyclic ADP-ribose
Cell Calcium·1999· 41 cited
Adenine nucleotide binding site on the inositol 1,4,5-triphosphate receptor bind caffeine but not adenophostin A or cADP-ribose.
VUBIR (Vrije Universiteit Brussel)·1999
ATP-induced Ca 2+ signals in bronchial epithelial cells
Pflügers Archiv - European Journal of Physiology·1998· 31 cited
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Frequent Co-authors

Humbert De Smedt(35), Jan B. Parys(35), Ludwig Missiaen(34), R. Casteels(22), Sara Vanlingen(13), Henk Sipma(7), Karlien Maes(7), Geert Callewaert(7), Nael Nadif Kasri(6), Patrick De Smet(5), Martin D. Bootman(4), Steven De Jonghe(4), Robert H. Henning(3), Karl Kunzelmann(3), Geert Bultynck(3), Gavin Clydesdale(3), F. X. Lemaire(3), Chong Shen(3), Louis Boon(3), Paul Rutgeerts(3)