Junaid Afzal

University of California, San Francisco — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index911citations54works4.22yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(10), Mitochondrial Function and Pathology(9), 3D Printing in Biomedical Research(7), Tissue Engineering and Regenerative Medicine(7), Cellular Mechanics and Interactions(4)

Publications54 total

Evidence for coopetition at the maternal–fetal interface shaping placental invasion
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Identifying genes underlying parallel evolution of stromal resistance to placental and cancer invasion
npj Systems Biology and Applications·2025Open Access
Identifying genes underlying parallel evolution of stromal resistance to placental and cancer invasion
2025
Extravillous trophoblasts reverse the decidualization induced increase in matrix production by secreting TGFβ antagonists Emilin-1 and Gremlin-1
Cells and Development·2025· 4 citedOpen Access
Scar matrix drives Piezo1 mediated stromal inflammation leading to placenta accreta spectrum
Nature Communications·2024· 16 citedOpen Access
Oscillatory hypoxia induced gene expression predicts low survival in human breast cancer patients
Molecular Carcinogenesis·2024· 7 citedOpen Access
Stable and oscillatory hypoxia differentially regulate invasibility of breast cancer associated fibroblasts
Mechanobiology in Medicine·2024· 6 citedOpen Access
Stable and Oscillatory Hypoxia Differentially Regulate Invasibility of Breast Cancer Associated Fibroblasts
2024· 2 citedOpen Access
Lactate in breast cancer cells is associated with evasion of hypoxia-induced cell cycle arrest and adverse patient outcome
Human Cell·2024· 5 citedOpen Access
Oscillatory Hypoxia Induced Unfolded Protein Folding Response Gene Expression Predicts Low Survival in Human Breast Cancer Patients
2024· 1 citedOpen Access
Frequent Premature Atrial Contractions Lead to Adverse Atrial Remodeling and Atrial Fibrillation in a Swine Model
Circulation·2023· 12 citedOpen Access
CRISPRing the hypertrophic cardiomyopathy: correcting one pathogenic variant at a time
Signal Transduction and Targeted Therapy·2023· 2 citedOpen Access
Metabolic Acidosis Results in Sexually Dimorphic Response in the Heart Tissue
Metabolites·2023· 4 citedOpen Access
Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells
Cell Systems·2022· 26 citedOpen Access
Paracrine HB-EGF signaling reduce enhanced contractile and energetic state of activated decidual fibroblasts by rebalancing SRF-MRTF-TCF transcriptional axis
Frontiers in Cell and Developmental Biology·2022· 16 citedOpen Access
Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes
Cell Reports·2022· 22 citedOpen Access
Tracing the cis-regulatory changes underlying the endometrial control of placental invasion
Proceedings of the National Academy of Sciences·2022· 19 citedOpen Access
Impaired Redox Homeostasis and Cardiovascular Aging
Healthy ageing and longevity·2021· 2 cited
Evolved Resistance to Placental Invasion Secondarily Confers Increased Survival in Melanoma Patients
Journal of Clinical Medicine·2021· 15 citedOpen Access
Incorporating and addressing testing bias within estimates of epidemic dynamics for SARS-CoV-2
BMC Medical Research Methodology·2021· 18 citedOpen Access
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Frequent Co-authors

Kshitiz Gupta(30), Yasir Suhail(22), Andre Levchenko(15), Yamin Liu(12), Wenqiang Du(10), M. Roselle Abraham(8), Ashkan Novin(8), Günter P. Wagner(7), Brian O’Rourke(6), Deok‐Ho Kim(5), Jamie Maziarz(5), Archer Hamidzadeh(5), Chi V. Dang(5), Styliani Vakrou(5), Ruchi Goyal(5), Maimon E. Hubbi(4), Angel Chan(4), Richard L. Wahl(4), B.M.W. Tsui(4), David Ellison(4)