Tomáš Klejch

Contipro (Czechia) — Czech Republic

Medicine · Health Sciences

7h-index100citations10works3.52yr avg
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Research Topics

HIV/AIDS drug development and treatment(4), Biochemical and Molecular Research(4), Glycosylation and Glycoproteins Research(3), Trypanosoma species research and implications(3), Carbohydrate Chemistry and Synthesis(2)

Publications10 total

Thiol addition to hyaluronic acid oligomer non-reducing terminus - synthesis, analysis, stability, and unexpected stereoselectivity
Carbohydrate Polymers·2025
Enzymatically stable unsaturated hyaluronan-derived oligosaccharides with selective cytostatic properties
Carbohydrate Polymers·2024· 7 cited
Modified hyaluronic acid with enhanced resistance to degradation
Carbohydrate Polymers·2023· 18 cited
Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases
Journal of Medicinal Chemistry·2022· 7 citedOpen Access
Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro
Scientific Reports·2021· 11 citedOpen Access
Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation
European Journal of Medicinal Chemistry·2019· 16 citedOpen Access
Selectivity of original C-hexopyranosyl calix[4]arene conjugates towards lectins of different origin
Carbohydrate Research·2018· 15 cited
Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases
Tetrahedron·2018· 12 cited
Calix[4]arenes containing a ureido functionality on the lower rim as highly efficient receptors for anion recognition
New Journal of Chemistry·2016· 14 cited
CCDC 1471641: Experimental Crystal Structure Determination
The Cambridge Structural Database·2016Open Access

Frequent Co-authors

Luke W. Guddat(4), Dana Hocková(4), Radovan Buffa(3), Vladimı́r Velebný(3), Dianne T. Keough(3), Zlatko Janeba(3), Pavel Lhoták(3), Hana Vágnerová(2), Kristina Nešporová(2), Radek Pohl(2), Jan Slavíček(2), Oldřích Hudeček(2), Václav Eigner(2), Natalia Andrea Gutierrez(2), Petra Cuřínová(2), Eva Doleželová(2), Alena Zı́ková(2), Jiří Bednařík(2), Martina Brandejsová(2), František Fiala(2)