Eva Doleželová

Institute of Parasitology — Czech Republic

Medicine · Health Sciences

10h-index609citations21works1.32yr avg
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Research Topics

Trypanosoma species research and implications(13), Biochemical and Molecular Research(11), HIV/AIDS drug development and treatment(9), Neurobiology and Insect Physiology Research(4), ATP Synthase and ATPases Research(3)

Publications21 total

Assessment of Mitochondrial Membrane Potential in Intact and Detergent-Permeabilized Trypanosoma brucei Insect and Bloodstream Forms
Methods in molecular biology·2026Open Access
Reversal of ATP synthase is a key attribute for cellular differentiation of the <i>Trypanosoma brucei</i> insect forms
2025Open Access
FOF1-ATP synthase: When it pays to go in reverse
Biochimica et Biophysica Acta (BBA) - Bioenergetics·2024
Development of Prolinol Containing Inhibitors of Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design
Journal of Medicinal Chemistry·2024· 5 citedOpen Access
Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase
European Journal of Medicinal Chemistry·2022· 5 cited
Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases
Journal of Medicinal Chemistry·2022· 7 citedOpen Access
C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase
European Journal of Medicinal Chemistry·2021· 5 cited
Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro
Scientific Reports·2021· 11 citedOpen Access
Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides
ACS Infectious Diseases·2021· 5 cited
Synthesis and anti-trypanosomal activity of 3′-fluororibonucleosides derived from 7-deazapurine nucleosides
Bioorganic & Medicinal Chemistry Letters·2021· 8 cited
Developmental regulation of edited CYb and COIII mitochondrial mRNAs is achieved by distinct mechanisms in Trypanosoma brucei
Nucleic Acids Research·2020· 14 citedOpen Access
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
PLoS Biology·2020· 44 citedOpen Access
Crystal structures of <i>Trypanosoma brucei</i> hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with <scp>IMP</scp>,<scp> GMP</scp> and <scp>XMP</scp>
FEBS Journal·2019· 10 citedOpen Access
Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery
PLoS neglected tropical diseases·2018· 49 citedOpen Access
Equilibrative Nucleoside Transporter 2 Regulates Associative Learning and Synaptic Function in<i>Drosophila</i>
Journal of Neuroscience·2010· 38 citedOpen Access
Rhythm Defects Caused by Newly Engineered Null Mutations in Drosophila's <i>cryptochrome</i> Gene
Genetics·2007· 161 citedOpen Access
A Drosophila adenosine receptor activates cAMP and calcium signaling
Insect Biochemistry and Molecular Biology·2007· 80 cited
Principles and Problems Revolving Round Rhythm-related Genetic Variants
Cold Spring Harbor Symposia on Quantitative Biology·2007· 5 citedOpen Access
Use of two transcription starts in the <i>G6PD</i> gene of the bark beetle <i>Ips typographus</i>
Insect Molecular Biology·2006· 4 citedOpen Access
A Role for Adenosine Deaminase in Drosophila Larval Development
PLoS Biology·2005· 103 citedOpen Access
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Frequent Co-authors

Alena Zı́ková(13), Dana Hocková(6), Michal Žurovec(5), Luke W. Guddat(5), Dianne T. Keough(4), Martina Slapničková(4), Peter J. Bryant(3), Eva Tloušťová(3), Zlatko Janeba(3), Tomáš Doležal(2), D. Teran(2), Petr Špaček(2), Michaela Kunzová(2), Brian Panicucci(2), Tomáš Klejch(2), Radek Pohl(2), Michal Hocek(2), Gordon J. King(2), Lenka Poštová Slavětínská(2), David Doležel(1)