Alysson R. Muotri

University of California San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

71h-index21.6kcitations327works3.82yr avg
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Research Topics

Pluripotent Stem Cells Research(71), Genetics and Neurodevelopmental Disorders(67), CRISPR and Genetic Engineering(53), Autism Spectrum Disorder Research(30), Chromosomal and Genetic Variations(24)

Publications326 total

Human milk oligosaccharides promote synaptogenesis and neurite outgrowth in human cortical organoids
Biochemistry and Biophysics Reports·2026Open Access
Connexin-43 Restoration Alleviates Desmosomal Arrhythmogenic Cardiomyopathy
Circulation Heart Failure·2026Open Access
MeCP2 regulates telencephalic development in human cerebral organoids
Cell Reports·2025· 1 citedOpen Access
Dormant viral pathways underlie space-induced neural senescence
2025
Interregional human assembloids recapitulate fetal brain morphologies and enhance neuronal complexity
2025Open Access
Human ancestors were exposed to lead millions of years ago, and it shaped our evolution
2025
Impact of intermittent lead exposure on hominid brain evolution
Science Advances·2025· 3 citedOpen Access
Trisomy 21 Disrupts Thyroid Hormones Signaling During Human iPSC-Derived Neural Differentiation In Vitro
Cells·2025Open Access
Nanobioreactor detection of space-associated hematopoietic stem and progenitor cell aging
Cell stem cell·2025· 4 citedOpen Access
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics
Nature Communications·2025· 3 citedOpen Access
Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism
Molecular Psychiatry·2025· 2 cited
Convergent activation of the integrated stress response and ER–mitochondria uncoupling in VAPB-associated ALS
EMBO Molecular Medicine·2025· 1 citedOpen Access
Abstract Fri009: Connexin-43 Gene Therapy Targets Desmosomal Gene Expression To Rescue Cardiac End-Stage Deficits in Mouse and Human Models of Arrhythmogenic Cardiomyopathy
Circulation Research·2025· 1 cited
Deciphering Complexity in Human Brain Organoids via a Novel Hurst Exponent Estimation
Physical Review Letters·2025
A Cross-Correction Gene Therapy Approach for CDKL5 Deficiency Disorder Improves the Pathological Phenotype of CDD Patient-Derived Cortical Organoids
Preprints.org·2025Open Access
Graphene-polymer nanofibers enable optically induced electrical responses in stem cell-derived electrically excitable cells and brain organoids
Biomaterials·2025· 4 citedOpen Access
Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex
UNC Libraries·2025Open Access
A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex
UNC Libraries·2025Open Access
A modular CRISPRa system for molecular therapy of <i>FOXG1</i> syndrome
NAR Molecular Medicine·2025· 1 citedOpen Access
Author Reply to Peer Reviews of Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis
2025
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Frequent Co-authors

Fred H. Gage(28), Maria C. Marchetto(18), G Yeo(9), Cleber A. Trujillo(9), Priscilla D. Negraes(5), Nicole G. Coufal(5), Roberto H. Herai(5), Pinar Mesci(5), Jonathan Sebat(5), Cassiano Carromeu(4), John V. Moran(4), Kinichi Nakashima(4), Ángela Macia(4), Lilia M. Iakoucheva(4), José L. García-Pérez(4), Isabella Rodrigues Fernandes(3), Beatriz Freitas(3), Sarah Romero(3), Patrícia Cristina Baleeiro Beltrão-Braga(3), Allan Acab(3)