Fred H. Gage

Salk Institute for Biological Studies — United States

Neuroscience · Life Sciences

219h-index196.1kcitations1.1kworks19.12yr avg
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Research Topics

Neurogenesis and neuroplasticity mechanisms(393), Nerve injury and regeneration(172), Neuroscience and Neuropharmacology Research(160), Pluripotent Stem Cells Research(159), Memory and Neural Mechanisms(106)

Publications1.1k total

Retrotransposon Activation in the Aged and Alzheimer’s Disease Brain Examined by Nanopore Long-read DNA Sequencing
2025Open Access
Omnidirectional 3D Printing of Anisotropic Nanofibrous Peptide Hydrogels
2025Open Access
The need for a global effort to attend to human neural organoid and assembloid research
Science·2025· 1 cited
Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice
BMC Neuroscience·2025Open Access
AGO1 in neural progenitor cells orchestrates brain development and sociability via LIN28A-REELIN axis
2025Open Access
Differential effects of lithium on metabolic dysfunctions in astrocytes derived from bipolar disorder patients
Molecular Psychiatry·2025· 2 citedOpen Access
Low-frequency genetic variants in GAK enhance Golgi function and protect against Parkinson’s disease
2025Open Access
CK2 inhibition suppresses glial inflammation in the brain
2025· 1 citedOpen Access
Scaffold hopping and sidechain modification from a flavone scaffold lead to discovery of potent, selective CK2A2 inhibitors with favorable properties for CNS activity
Bioorganic & Medicinal Chemistry·2025· 2 cited
New neurons are born in the adult human brain
Nature Medicine·2025· 3 cited
Adult Neurogenesis
2025
A framework for neural organoids, assembloids and transplantation studies
Nature·2024· 66 citedOpen Access
Adult Neurogenesis in the Human Dentate Gyrus
Hippocampus·2024· 21 citedOpen Access
miR-124 coordinates metabolic regulators acting at early stages of human neurogenesis
Communications Biology·2024· 12 citedOpen Access
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Science·2024· 153 citedOpen Access
Modeling Alzheimer’s disease using human cell derived brain organoids and 3D models
Frontiers in Neuroscience·2024· 20 citedOpen Access
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
2024· 5 citedOpen Access
Neuronal senescence may drive brain aging
Science·2024· 49 citedOpen Access
High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer
Nature Communications·2024· 53 citedOpen Access
Protocol for the San Diego Nathan Shock Center Clinical Cohort: a new resource for studies of human aging
BMJ Open·2024· 2 citedOpen Access
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Frequent Co-authors

Gerd Kempermann(8), Henriette van Praag(7), Theo D. Palmer(5), H. Georg Kuhn(4), Yangling Mu(4), Ulrike Blömer(3), Inder M. Verma(3), Christopher K. Glass(3), Beate Winner(3), Maria C. Marchetto(3), Chunmei Zhao(3), Brian R. Christie(3), Sebastian Jessberger(3), Alysson R. Muotri(3), Daniel A. Peterson(2), Luigi Naldini(2), Didier Trono(2), Kaoru Saijo(2), Wei Deng(2), Irving L. Weissman(2)