Christoph Maack

Medicine · Health Sciences

61h-index19.4kcitations324works6.22yr avg
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Research Topics

Cardiovascular Function and Risk Factors(87), Mitochondrial Function and Pathology(77), Heart Failure Treatment and Management(60), Cardiac electrophysiology and arrhythmias(52), Cardiac Ischemia and Reperfusion(38)

Publications323 total

Models of the Human Heart for Biomedical Research: Opportunities and Challenges
Preprints.org·2026Open Access
Abstract 4339547: Nicotinamide Nucleoside Transhydrogenase (NNT) loss-of-function attenuates oxidative stress-associated myocardial fibrosis and diastolic dysfunction in cardiometabolic HFpEF
Circulation·2025
Enhanced iPSC Cardiomyocyte Maturation via Combined 3D-Culture and Metabolic Cues
2025· 1 citedOpen Access
Adaptive mechanisms in pancreatic islets counteract mitochondrial dysfunction in Barth syndrome
Diabetologia·2025Open Access
Hypercontractility and Oxidative Stress Drive Creatine Kinase Dysfunction in Hypertrophic Cardiomyopathy
Circulation·2025· 3 citedOpen Access
CAMK2-NR4A1 signaling initiates metabolic substrate switching to induce heart failure with reduced ejection fraction
2025Open Access
Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation
Circulation Research·2025· 5 citedOpen Access
Interferon gamma signaling drives cardiac metabolic rewiring
2025· 2 citedOpen Access
OC21 - Additive effects of semaglutide and peptide YY3-36 dual agonism on HFpEF: focus on excitation-contraction coupling and mitochondrial function in obese rats
European Journal of Endocrinology·2025Open Access
Tafazzin-Mediated Cardiolipin Remodeling Controls Metabolic Stress Response and Effector Function of Inflammatory T Cells
2025Open Access
C-type natriuretic peptide attenuates enhanced glycolysis and de novo pyrimidine synthesis in pericytes of patients with pulmonary arterial hypertension
Communications Biology·2025· 1 citedOpen Access
Calmodulin enhancement of mitochondrial calcium uniporter function in isolated mitochondria
Cell Calcium·2025Open Access
ATP-Citrate Lyase in Heart Failure
JACC Basic to Translational Science·2025Open Access
Metabolic alterations in heart failure
Nature Reviews Cardiology·2025· 3 cited
Cardiac intermediary metabolism in heart failure: substrate use, signalling roles and therapeutic targets
Nature Reviews Cardiology·2025· 15 citedOpen Access
Mechano-energetic uncoupling in heart failure
Nature Reviews Cardiology·2025· 15 citedOpen Access
How to Facilitate Seamless Translation from Basic Concepts to New Heart Failure Drugs. A Scientific Statement of the Heart Failure Association of the ESC
European Journal of Heart Failure·2025· 5 citedOpen Access
Metabolic alterations in human hypertrophic cardiomyopathy
The Journal of Cardiovascular Aging·2025· 1 citedOpen Access
Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF
Circulation Research·2025· 13 cited
Sex-specific effects of different dietary compositions and NO-synthase inhibition on mitochondrial respiration and cellular redox state in HFPEF and MASLD
Endocrine Abstracts·2025
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Frequent Co-authors

Rudolf A. de Boer(10), Johann Bauersachs(10), Michael Kohlhaas(10), Carlo G. Tocchetti(8), Frank Ruschitzka(8), Michael Böhm(8), Johannes Backs(8), Petar Seferović(7), Edoardo Bertero(7), Alexander Nickel(7), Brian O’Rourke(7), Stéphane Heymans(7), Dirk L. Brutsaert(6), Adam Torbicki(5), Alexander R. Lyon(5), Andrew J.S. Coats(5), Thomas Thum(5), Gilles W. De Keulenaer(5), Lorenz Lehmann(5), Stavros Konstantinides(4)