Rosaria Luciani

University of Modena and Reggio Emilia — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.2kcitations68works0.02yr avg
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Research Topics

Biochemical and Molecular Research(31), Colorectal Cancer Treatments and Studies(18), Trypanosoma species research and implications(14), Synthesis and Biological Evaluation(14), Research on Leishmaniasis Studies(13)

Publications68 total

Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach
Journal of Medicinal Chemistry·2025Open Access
Design of 2-aminobenzothiazole derivatives targeting trypanosomatid PTR1 by a multidisciplinary fragment hybridization approach
2025Open Access
Design of 2-aminobenzothiazole derivatives targeting trypanosomatid PTR1 by a multidisciplinary fragment-based approach
2025Open Access
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents
European Journal of Medicinal Chemistry·2023· 5 citedOpen Access
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents
Journal of Medicinal Chemistry·2023· 10 citedOpen Access
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
eLife·2022· 13 citedOpen Access
Author response: Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
2022Open Access
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1
Journal of Medicinal Chemistry·2022· 17 citedOpen Access
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1
2022· 1 citedOpen Access
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1
2022· 1 citedOpen Access
Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases
Pharmaceuticals·2021· 7 citedOpen Access
Multitarget, Selective Compound Design Yields Picomolar Inhibitors of a Kinetoplastid Pteridine Reductase 1
2021Open Access
Multitarget, Selective Compound Design Yields Picomolar Inhibitors of a Kinetoplastid Pteridine Reductase 1
2021Open Access
Disrupters of the Thymidylate Synthase Homodimer Accelerate Its Proteasomal Degradation and Inhibit Cancer Growth.
2021Open Access
Disrupters of the Thymidylate Synthase Homodimer Accelerate Its Proteasomal Degradation and Inhibit Cancer Growth.
2021· 1 citedOpen Access
Multitarget, Selective Compound Design Yields Picomolar Inhibitors of a Kinetoplastid Pteridine Reductase 1
2020Open Access
Multitarget, Selective Compound Design Yields Picomolar Inhibitors of a Kinetoplastid Pteridine Reductase 1
2020Open Access
Multitarget, Selective Compound Design Yields Picomolar Inhibitors of a Kinetoplastid Pteridine Reductase 1
2020Open Access
Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth
Molecules·2019· 5 citedOpen Access
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics
European Journal of Medicinal Chemistry·2019· 27 citedOpen Access
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Frequent Co-authors

Maria Paola Costi(43), Stefania Ferrari(34), Stefano Mangani(23), Cecilia Pozzi(21), Anabela Cordeiro‐da‐Silva(16), Nuno Santarém(15), Pasquale Linciano(14), Matteo Santucci(14), Luca Costantino(13), Gaetano Marverti(12), Glauco Ponterini(12), Sheraz Gul(12), Bernhard Ellinger(12), Alberto Venturelli(11), Rebecca C. Wade(11), Puneet Saxena(10), Gesa Witt(10), Giacomo Landi(9), Maria Kuzikov(9), Antonio Quotadamo(9)