Lennart Lindfors

Advanced Pharma — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index3.9kcitations61works13.62yr avg
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Research Topics

RNA Interference and Gene Delivery(20), Drug Solubulity and Delivery Systems(16), Lipid Membrane Structure and Behavior(15), Crystallization and Solubility Studies(14), Nanoparticle-Based Drug Delivery(7)

Publications61 total

Effects of Serum Incubation on Lipid Nanoparticle PEG Shedding, mRNA Retention, and Membrane Interactions
ACS Applied Materials & Interfaces·2025· 2 citedOpen Access
Cellular and biophysical barriers to lipid nanoparticle mediated delivery of RNA to the cytosol
Nature Communications·2025· 27 citedOpen Access
Multiparametric functional characterization of individual lipid nanoparticles using surface-sensitive light-scattering microscopy
Proceedings of the National Academy of Sciences·2025· 9 citedOpen Access
Correction to “Selecting Counterions to Improve Ionized Hydrophilic Drug Encapsulation in Polymeric Nanoparticles”
Molecular Pharmaceutics·2025Open Access
Targeted delivery of mRNA to the heart via extracellular vesicles or lipid nanoparticles
2025· 1 citedOpen Access
On the Ostwald ripening of crystalline and amorphous nanoparticles
Soft Matter·2025· 23 citedOpen Access
Ph Affects Structure of Mrna:Lipid Nanoparticle
Research at the University of Copenhagen (University of Copenhagen)·2025
Combining SAXS analysis and MD simulation to determine structure and hydration of ionizable lipid hexagonal phases
Soft Matter·2025Open Access
Time-Resolved Inspection of Ionizable Lipid-Facilitated Lipid Nanoparticle Disintegration and Cargo Release at an Early Endosomal Membrane Mimic
ACS Nano·2024· 27 citedOpen Access
Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics
Molecular Aspects of Medicine·2024· 35 citedOpen Access
Cellular and biophysical barriers to lipid nanoparticle mediated delivery of RNA to the cytosol
2024· 5 citedOpen Access
Time Resolved Inspection of Ionizable-Lipid Facilitated Lipid Nanoparticle Disintegration and Cargo Release at an Endosomal Membrane Mimic
2024Open Access
Lipid shape and packing are key for optimal design of pH-sensitive mRNA lipid nanoparticles
Proceedings of the National Academy of Sciences·2024· 47 citedOpen Access
The <i>In Vivo</i> Fate of Polycatecholamine Coated Nanoparticles Is Determined by a Fibrinogen Enriched Protein Corona
ACS Nano·2023· 12 cited
pH-dependent structural transitions in cationic ionizable lipid mesophases are critical for lipid nanoparticle function
Proceedings of the National Academy of Sciences·2023· 109 citedOpen Access
Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions
Advanced Science·2023· 76 citedOpen Access
Selecting Counterions to Improve Ionized Hydrophilic Drug Encapsulation in Polymeric Nanoparticles
Molecular Pharmaceutics·2023· 11 cited
Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion
ACS Nano·2022· 62 citedOpen Access
Frequency-dependent signaling in cardiac myocytes
Frontiers in Physiology·2022· 1 citedOpen Access
Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immunostaining
RNA·2021· 4 citedOpen Access
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Frequent Co-authors

Marianna Yanez Arteta(9), Urban Skantze(9), Pia Skantze(8), Jan Westergren(7), Kalle Sigfridsson(7), Bertil Abrahamsson(6), Stefano Bartesaghi(5), Ulf Olsson(5), Alan Sabirsh(5), Yujia Jing(5), Sture Nordholm(5), Fredrik Höök(5), Aleksandra P. Dabkowska(4), Hadi Valadi(4), Andreas Höijer(4), Shalini Andersson(4), Sara Carlert(4), Kai Lüder(4), Erik Michaëlsson(4), Gustav Emilsson(4)