Stefano Bartesaghi

AstraZeneca (Sweden) — Sweden

Medicine · Health Sciences

23h-index4.2kcitations57works3.52yr avg
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Research Topics

Adipose Tissue and Metabolism(13), RNA Interference and Gene Delivery(8), Lipid metabolism and biosynthesis(7), Neuroscience and Neuropharmacology Research(5), Glioma Diagnosis and Treatment(4)

Publications57 total

Inhibition of IL-33 in Diabetic Kidney Disease
Journal of the American Society of Nephrology·2025
Abstract 4137311: Inhibition of IL-33 by tozorakimab in patients with diabetic kidney disease: Cardiovascular insights from FRONTIER-1
Circulation·2024· 1 cited
#2267 IL-33 Inhibition with tozorakimab for diabetic kidney disease: a randomized, placebo-controlled phase 2b study
Nephrology Dialysis Transplantation·2024· 1 citedOpen Access
Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease
Kidney International Reports·2024· 12 citedOpen Access
NRF2 is essential for adaptative browning of white adipocytes
Redox Biology·2023· 12 citedOpen Access
#5413 FRONTIER-1: A PHASE 2B STUDY OF IL-33 BLOCKADE IN DIABETIC KIDNEY DISEASE
Nephrology Dialysis Transplantation·2023· 1 citedOpen Access
The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes
Journal of Biological Chemistry·2023· 11 citedOpen Access
SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation
Metabolism Open·2023· 3 citedOpen Access
ELEVATED ADIPOCYTE MEMBRANE PHOSPHOLIPID SATURATION DOES NOT COMPROMISE INSULIN SIGNALING
2023Open Access
ELEVATED ADIPOCYTE MEMBRANE PHOSPHOLIPID SATURATION DOES NOT COMPROMISE INSULIN SIGNALING
2022Open Access
ELEVATED ADIPOCYTE MEMBRANE PHOSPHOLIPID SATURATION DOES NOT COMPROMISE INSULIN SIGNALING
2022Open Access
Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling
Diabetes·2022· 7 citedOpen Access
Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice
Molecular Therapy — Nucleic Acids·2022· 36 citedOpen Access
Knockdown of sarcolipin (SLN) impairs substrate utilization in human skeletal muscle cells
Molecular Biology Reports·2022· 4 citedOpen Access
Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immunostaining
RNA·2021· 4 citedOpen Access
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
The Journal of Cell Biology·2021· 174 citedOpen Access
Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immuno-staining
2021· 1 citedOpen Access
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein
Molecular Therapy — Nucleic Acids·2021· 84 citedOpen Access
SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells
Current Research in Pharmacology and Drug Discovery·2021· 2 citedOpen Access
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale
2020· 13 citedOpen Access
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Frequent Co-authors

Barbara Viviani(12), Marina Marinovich(12), Xiaorong Peng(12), C. Galli(11), Paolo Salomoni(9), Emanuela Corsini(8), Simonetta Wallin(7), Pierluigi Nicotera(7), Marianna Yanez Arteta(6), Lennart Lindfors(6), Henrik Palmgren(6), Shalini Andersson(6), Anne‐Christine Andréasson(6), Mohammad Bohlooly‐Y(6), Marco Binaglia(5), David Dinsdale(5), Sebastian Brandner(5), Andreas Höijer(5), Alexis Hofherr(5), Viknesh Selvarajah(5)