Laura Israël

Novartis (Switzerland) — Switzerland

Immunology and Microbiology · Life Sciences

15h-index2.2kcitations25works0.02yr avg
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Research Topics

Immune Response and Inflammation(9), NF-κB Signaling Pathways(8), interferon and immune responses(6), Immunodeficiency and Autoimmune Disorders(5), Cell death mechanisms and regulation(4)

Publications25 total

Assessment of antigen-specific T cell recall responses in non-human primates using a composite AIM assay
Frontiers in Immunology·2025Open Access
Pitfalls of Machine Learning based Personnel Selection - Fairness, Transparency and Data Quality
2021· 5 citedOpen Access
Measuring Implicit Motives With the Picture Story Exercise (PSE): Databases of Expert-Coded German Stories, Pictures, and Updated Picture Norms
2021· 9 citedOpen Access
CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo
Oncogenesis·2021· 17 citedOpen Access
Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet Elimination, in Mice
Arthritis & Rheumatology·2020· 8 cited
Emotion Prediction with Weighted Appraisal Models – Validating a Psychological Theory of Affect
2020· 2 citedOpen Access
Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell–Mediated Autoimmunity
The Journal of Immunology·2019· 21 citedOpen Access
An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
Nature Chemical Biology·2019· 65 cited
Clinical and Genetic Heterogeneity of CARD14 Mutations in Psoriatic Skin Disease
Frontiers in Immunology·2018· 69 citedOpen Access
A CARD10-Dependent Tonic Signalosome Activates MALT1 Paracaspase and Regulates IL-17/TNF-α–Driven Keratinocyte Inflammation
Journal of Investigative Dermatology·2018· 20 cited
Ways and waves of MALT1 paracaspase activation
Cellular and Molecular Immunology·2017· 11 citedOpen Access
Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity
Cell·2017· 80 citedOpen Access
Inherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblasts
Proceedings of the National Academy of Sciences·2017· 56 citedOpen Access
Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation
PLoS ONE·2017· 29 citedOpen Access
A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4
Nature Immunology·2014· 81 citedOpen Access
Un nouveau défaut héréditaire chez l'homme (déficit en TIRAP)
theses.fr (ABES)·2013Open Access
Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency
Nature Immunology·2012· 461 citedOpen Access
IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4–, MyD88-, and TIRAP- but not UNC-93B–deficient patients
Blood·2012· 102 citedOpen Access
PS2-010. Human TIRAP deficiency in eight individuals from a large consanguineous family: A cause for predisposition to staphylococcal diseases?
Cytokine·2011
New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein
Blood·2011· 57 citedOpen Access
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Frequent Co-authors

Anne Puel(9), Capucine Pïcard(9), Jean‐Laurent Casanova(9), Maya Chrabieh(8), Laurent Abel(7), Frédéric Bornancin(7), Damien Chaussabel(4), Maureen Bardet(4), Thomas Calzascia(4), Jacinta Bustamante(3), Christine Bodemer(3), Elisabeth Israelsson(3), Avinash Abhyankar(3), Peter D. Arkwright(3), Stefanie Ginster(3), Adeline Unterreiner(3), Kea Martin(3), Sophie Cypowyj(2), Jill F. Wright(2), Luyan Liu(2)