Robert Schwarcz

University of Maryland, Baltimore — United States

Neuroscience · Life Sciences

74h-index21.5kcitations260works6.82yr avg
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Research Topics

Tryptophan and brain disorders(160), Stress Responses and Cortisol(73), Neuroscience and Neuropharmacology Research(66), Neuroendocrine regulation and behavior(56), Genetic Neurodegenerative Diseases(37)

Publications260 total

Kynurenine pathway dysregulation via loss of QPRT drives declines in activity and altered metabolism in mice
GeroScience·2025· 1 citedOpen Access
Kynurenic Acid Synthesis from D-Kynurenine in the Cerebellum: A Distinct Role of D-Amino Acid Oxidase
Cells·2025Open Access
Adrenalectomy exacerbates stress-induced impairment in fear discrimination: A causal role for kynurenic acid?
Biochemical Pharmacology·2024· 5 cited
The Probiotic Lactobacillus reuteri Preferentially Synthesizes Kynurenic Acid from Kynurenine
International Journal of Molecular Sciences·2024· 15 citedOpen Access
The Tryptophan Metabolite Indole-3-Propionic Acid Raises Kynurenic Acid Levels in the Rat Brain In Vivo
International Journal of Tryptophan Research·2024· 13 citedOpen Access
Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow
Neuropsychopharmacology·2023· 18 citedOpen Access
Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex‐specific pattern
Aging Cell·2023· 7 citedOpen Access
Alterations in rat prefrontal cortex kynurenic acid levels are involved in the enduring cognitive dysfunctions induced by tetrahydrocannabinol exposure during the adolescence
Frontiers in Psychiatry·2022· 12 citedOpen Access
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane
Biomedicines·2022· 7 citedOpen Access
Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid
Pharmaceuticals·2022· 17 citedOpen Access
Expert Recommendations on the Use of Hyaluronic Acid Filler for Tear Trough Rejuvenation.
PubMed·2022· 9 cited
Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma
Antioxidants·2022· 23 citedOpen Access
A single prenatal lipopolysaccharide injection has acute, but not long‐lasting, effects on cerebral kynurenine pathway metabolism in mice
European Journal of Neuroscience·2021· 5 citedOpen Access
Author response for "A single prenatal lipopolysaccharide injection has acute, but not long‐lasting, effects on cerebral kynurenine pathway metabolism in mice"
2021Open Access
Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?
Frontiers in Pharmacology·2021· 3 citedOpen Access
Subchronic N-acetylcysteine Treatment Decreases Brain Kynurenic Acid Levels and Improves Cognitive Performance in Mice
Antioxidants·2021· 27 citedOpen Access
The Discovery and Characterization of Targeted Perikaryal-Specific Brain Lesions With Excitotoxins
Frontiers in Neuroscience·2020· 8 citedOpen Access
N-Acetylcysteine Inhibits Kynurenine Aminotransferase II
Neuroscience·2020· 33 citedOpen Access
Stress-induced impairment in fear discrimination is causally related to increased kynurenic acid formation in the prefrontal cortex
Psychopharmacology·2020· 25 citedOpen Access
Prenatal THC exposure raises kynurenic acid levels in the prefrontal cortex of adult rats
Progress in Neuro-Psychopharmacology and Biological Psychiatry·2020· 28 citedOpen Access
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Frequent Co-authors

Paolo Guidetti(13), Korrapati V. Sathyasaikumar(7), Hui‐Qiu Wu(6), William O. Whetsell(6), Arash Rassoulpour(6), Paul J. Muchowski(5), Edson X. Albuquerque(5), Joseph T. Coyle(4), Roberto Pellicciari(4), Flaviano Giorgini(4), Etsuo Okuno(4), Edna F. R. Pereira(3), Rosalinda C. Roberts(3), Francesca M. Notarangelo(3), Alan C. Foster(3), Ikwunga Wonodi(3), Michael T. Sapko(3), John P. Bruno(2), Edward W. Green(2), Carlo Breda(2)