Roberto Pellicciari

Bridge Pharma (United States) — United States

Medicine · Health Sciences

57h-index16.6kcitations335works0.12yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(79), Neuroscience and Neuropharmacology Research(50), Chemical Synthesis and Analysis(30), Cyclopropane Reaction Mechanisms(28), PARP inhibition in cancer therapy(27)

Publications335 total

#2315 TES-AKI-01 preserves renal function in a rat model of ischemia-reperfusion injury
Nephrology Dialysis Transplantation·2025
879: FXR AGONIST INT-787 INHIBITS INFLAMMATION, FIBROSIS, SENESCENCE, AND APOPTOSIS ARREST IN HUMAN CHOLANGIOCYTES MODELING PSC
Gastroenterology·2025
Su1635: FARNESOID X RECEPTOR AGONIST INT-787 EXHIBITS HIGH INTESTINAL LOCALIZATION
Gastroenterology·2025
Su1618: FARNESOID X RECEPTOR AGONIST INT-787 PROTECTS HUMAN LIVER ORGANOIDS FROM ALCOHOL-INDUCED INJURY
Gastroenterology·2025
Abstract 3135: First-in-class NR2F6 antagonist TES-ONC-07 enhances anti-cancer host immunity reducing tumor growth in a “cold” cancer model
Cancer Research·2025
Multimodal assessment of the skin-nerve-axis identifies specific patterns in patients with cholestatic liver disease-associated pruritus
Zeitschrift für Gastroenterologie·2025
TOP-313 Farnesoid X receptor agonist INT-787 protects human liver organoids from alcohol-induced injury
Journal of Hepatology·2024
THU-316 Farnesoid X receptor agonist INT-787 exhibits high intestinal localization
Journal of Hepatology·2024· 1 cited
Serendipity meets synergism: differential enantiomer activities of a RAD51-BRCA2 disruptor towards a more robust synthetic lethality in pancreatic cancer
2024Open Access
Discovery and Structure–Activity Relationships of Novel <i>ss</i>DAF-12 Receptor Modulators
Journal of Medicinal Chemistry·2024Open Access
Structural Basis of Fxr Partial Agonism by Bile Acid Analogues: Synthesis, Sar and Pharmacological Profile of Obeticholic Acid Derivatives
SSRN Electronic Journal·2024Open Access
Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives
European Journal of Medicinal Chemistry·2023· 3 citedOpen Access
Data from Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy
2023Open Access
Supplementary Figures S1-9, Tables S1 and 2 from Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy
2023Open Access
Data from Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy
2023Open Access
Supplementary Figures S1-9, Tables S1 and 2 from Targeting the MDM2/MDM4 Interaction Interface as a Promising Approach for p53 Reactivation Therapy
2023Open Access
Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists
International Journal of Molecular Sciences·2023· 4 citedOpen Access
Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells
European Journal of Medicinal Chemistry·2022· 17 citedOpen Access
Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites
European Journal of Medicinal Chemistry·2022· 5 citedOpen Access
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
Immunity·2022· 106 citedOpen Access
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Frequent Co-authors

Gabriele Costantino(14), Antimo Gioiello(11), Kristina Schoonjans(10), Antonio Macchiarulo(9), Stefano Fiorucci(9), Flavio Moroni(9), Emidio Camaioni(8), Johan Auwerx(7), Maura Marinozzi(7), Mark Pruzanski(6), Charles Thomas(5), Antonio Morelli(5), Robert Schwarcz(5), Elisabetta Antonelli(5), Barbara Renga(5), Benedetto Natalini(5), Bahman M. Sadeghpour(5), Giovanni Rizzo(4), Timothy M. Willson(4), Andrea Mencarelli(4)