Yong‐Chen Lu

Winthrop Rockefeller Foundation — United States

Medicine · Health Sciences

28h-index12.2kcitations90works2.22yr avg
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Research Topics

CAR-T cell therapy research(58), Cancer Immunotherapy and Biomarkers(41), Immunotherapy and Immune Responses(37), Cancer Research and Treatments(15), Immune Cell Function and Interaction(14)

Publications90 total

Isolation of mitochondrial mutation-specific T cell receptors
The Journal of Immunology·2025· 3 cited
A Randomized Double-Blind Phase 2 Clinical Trial Treating Cervical Intraepithelial Neoplasia 2/3 with PepCan or <i>Candida</i>
2025· 2 citedOpen Access
Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
Gut·2025· 2 citedOpen Access
376 Inhibition of GSK3β-mediated 53BP1 T334 phosphorylation in T cells enhances infiltration and cytotoxicity against head and neck squamous cell carcinoma
Regular and Young Investigator Award Abstracts·2024Open Access
Immune responses in a phase 2 clinical trial of peptide-based therapeutic human papillomavirus vaccine, PepCan, versus <i>Candida</i> adjuvant alone in treating cervical intraepithelial neoplasia 2/3.
Journal of Clinical Oncology·2024· 1 cited
Deciphering CD4<sup>+</sup> T cell‐mediated responses against cancer
Molecular Carcinogenesis·2024· 5 citedOpen Access
A peptide-based human papillomavirus therapeutic vaccine, PepCan, or <i>Candida</i> adjuvant alone in treatment of cervical intraepithelial neoplasia 2/3 (CIN2/3).
Journal of Clinical Oncology·2023· 2 cited
Supplementary Data from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
2023Open Access
Data from Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
2023Open Access
Supplementary Figures from Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
2023Open Access
Supplementary Table S2 from Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
2023Open Access
Data from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
2023Open Access
Supplementary Figures from Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
2023Open Access
Supplementary Table S5 from Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
2023Open Access
Data from Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
2023Open Access
Supplementary Figure from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors
2023Open Access
Supplementary Table S2 from Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
2023Open Access
Supplementary Tables 1 and 2 from Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
2023Open Access
Data from Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy
2023Open Access
Data from Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer
2023Open Access
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Frequent Co-authors

Paul F. Robbins(28), Steven A. Rosenberg(27), Zhili Zheng(17), Jared J. Gartner(16), Todd D. Prickett(15), Yong F. Li(11), Maria R. Parkhurst(10), James C. Yang(10), Satyajit Ray(10), Stephanie L. Goff(10), Nikolaos Zacharakis(8), Eric Tran(7), Anna Pasetto(7), Frank J. Lowery(7), Sri Krishna(6), Praveen D. Chatani(6), Biman C. Paria(6), Richard M. Sherry(6), Lee Jia(5), Mona El‐Gamil(5)