Steven A. Rosenberg

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

219h-index196.2kcitations1.6kworks7.22yr avg
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Research Topics

Immunotherapy and Immune Responses(831), CAR-T cell therapy research(783), Cancer Immunotherapy and Biomarkers(418), Immune Cell Function and Interaction(317), Virus-based gene therapy research(218)

Publications1.6k total

Identification of HLA class II-restricted T cell receptors against shared PIK3CA mutations in patients with epithelial cancers
Cancer Immunology Immunotherapy·2025Open Access
Selective expansion of T-cell receptor engineered T cells with increased stem-like phenotypes using neoantigen stimulation
Journal for ImmunoTherapy of Cancer·2025Open Access
379 Selection of CD103+CD31-CD8+ cells enriches tumor reactivity of tumor infiltrating lymphocytes (TIL) independent of personalized sequencing
Regular and Young Investigator Award Abstracts·2025Open Access
375  <i>KLF2</i> -overexpression imparts stemness onto dysfunctional neoantigen-reactive human tumor-infiltrating lymphocytes
Regular and Young Investigator Award Abstracts·2025Open Access
372 Cell surface marker-based enrichment of CD4+ neoantigen-reactive tumor infiltrating lymphocytes from metastatic epithelial cancers
Regular and Young Investigator Award Abstracts·2025Open Access
Zelig Eshhar (1941–2025): a tribute for a life for immunotherapy
Journal for ImmunoTherapy of Cancer·2025Open Access
Survival after anti-CD19 CAR T-cell therapy for B-cell non-Hodgkin lymphoma and CLL with 10 years of follow-up
Blood Advances·2025· 1 citedOpen Access
Adoptive Cell Transfer of Tumor-Infiltrating Lymphocytes for Metastatic Acral Lentiginous Melanoma
Journal of Clinical Oncology·2025· 1 cited
Publisher Correction: Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial
Nature Medicine·2025· 4 cited
Tumor-infiltrating lymphocyte immunotherapy comes of age: a journey of development in the Surgery Branch, NCI
Journal for ImmunoTherapy of Cancer·2025· 4 citedOpen Access
Neoantigen-specific tumor-infiltrating lymphocytes in gastrointestinal cancers: a phase 2 trial
Nature Medicine·2025· 35 citedOpen Access
Utilization of primary tumor samples for cancer neoantigen discovery
Journal for ImmunoTherapy of Cancer·2025· 3 citedOpen Access
405 Identification of HLA class II-restricted T cell receptors against shared PIK3CA mutations in patients with epithelial cancers
Regular and Young Investigator Award Abstracts·2024Open Access
344 Drug-regulatable, inducible, and membrane-bound interleukin 12 (IL-12TM-D) for use in adoptive cell therapies against advanced cancers
Regular and Young Investigator Award Abstracts·2024Open Access
447 Clinical factors associated with growth and reactivity of tumor infiltrating lymphocytes for adoptive cell transfer in patients with metastatic epithelial cancers
Regular and Young Investigator Award Abstracts·2024Open Access
367 CD8 coreceptor dependence in HLA class I neoantigen-targeted TCR therapy
Regular and Young Investigator Award Abstracts·2024Open Access
Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results
Nature Medicine·2024· 62 cited
Lymphocytes as a living drug for cancer
Science·2024· 15 cited
Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes
Journal for ImmunoTherapy of Cancer·2024· 27 citedOpen Access
Adoptive transfer of T lymphocytes retrovirally transduced to express personalized neoantigen reactive T cell receptors can mediate tumor regression in patients with metastatic colorectal cancer
2024Open Access
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Frequent Co-authors

Nicholas P. Restifo(20), Mark E. Dudley(19), Richard M. Sherry(15), James Chih‐Hsin Yang(14), James C. Yang(12), Paul F. Robbins(12), Suzanne L. Topalian(12), John R. Wunderlich(11), Udai S. Kammula(11), Donald E. White(10), Marybeth S. Hughes(10), Claudia A. Seipp(9), Richard A. Morgan(8), Carolyn M. Laurençot(8), Steven A. Feldman(7), Douglas J. Schwartzentruber(7), Giao Q. Phan(7), Sharon Mavroukakis(6), Michael T. Lotze(6), Richard E. Royal(6)