Steven A. Rosenberg

National Institutes of Health — United States

Immunology and Microbiology · Life Sciences

219h-index196.2kcitations1.6kworks7.22yr avg

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Research Topics

Immunotherapy and Immune Responses(831), CAR-T cell therapy research(783), Cancer Immunotherapy and Biomarkers(418), Immune Cell Function and Interaction(317), Virus-based gene therapy research(218)

Publications1.6k total

Abstract C106: IMPACT restrains immuno-metabolic GCN1 signaling to govern pancreatic cancer metastasis

Cancer Research·2024

Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain

13 cited

Molecular Therapy·2023· 13 citedOpen Access

Abstract B007: Phenotypic Signatures of Circulating Neoantigen-Reactive CD8+ T Cells in Patients with Metastatic Cancers

Cancer Immunology Research·2023

Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers

69 cited

Cancer Cell·2023· 69 citedOpen Access

Adoptive Transfer of T Cells Genetically Engineered to Express T-Cell Receptors Targeting Neoantigens Arising from p53 and Ras Hotspot Mutations in Hematologic Malignancies

Blood·2023Open Access

366 Neoantigen-specific stimulation of T cells for effective cancer adoptive cell therapies

1 cited

Regular and Young Investigator Award Abstracts·2023· 1 citedOpen Access

369 Concurrent neoantigen vaccination enhances the antitumor effect of dysfunctional T cells during cell therapy

Regular and Young Investigator Award Abstracts·2023Open Access

921 ADGRG1 cell surface expression enriches for neoantigen-reactive CD4 lymphocytes from human tumors

Regular and Young Investigator Award Abstracts·2023Open Access

1216 Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers

Regular and Young Investigator Award Abstracts·2023Open Access

385 Selection of CD8+CD103+CD31- tumor infiltrating lymphocytes (TIL) from bulk cultures enriches tumor-specific reactivity in a patient-agnostic manner

Regular and Young Investigator Award Abstracts·2023Open Access

Data from Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy

2023Open Access

Supplementary Data from Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy

2023Open Access

Supplementary Data from Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy

2023Open Access

Supplementary Data from Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy

2023Open Access

Supplementary Data from Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy

2023Open Access

Data from Identification and Validation of T-cell Receptors Targeting RAS Hotspot Mutations in Human Cancers for Use in Cell-based Immunotherapy

2023Open Access

Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens

33 cited

Cancer Immunology Immunotherapy·2023· 33 citedOpen Access

Cell surface marker-based capture of neoantigen-reactive CD8+ T-cell receptors from metastatic tumor digests

24 cited

Journal for ImmunoTherapy of Cancer·2023· 24 citedOpen Access

Supplementary Data from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors

2023Open Access

Data from Single-Cell Transcriptome Analysis Reveals Gene Signatures Associated with T-cell Persistence Following Adoptive Cell Therapy

2023Open Access

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Frequent Co-authors

Nicholas P. Restifo(20), Mark E. Dudley(19), Richard M. Sherry(15), James Chih‐Hsin Yang(14), James C. Yang(12), Paul F. Robbins(12), Suzanne L. Topalian(12), John R. Wunderlich(11), Udai S. Kammula(11), Donald E. White(10), Marybeth S. Hughes(10), Claudia A. Seipp(9), Richard A. Morgan(8), Carolyn M. Laurençot(8), Steven A. Feldman(7), Douglas J. Schwartzentruber(7), Giao Q. Phan(7), Sharon Mavroukakis(6), Michael T. Lotze(6), Richard E. Royal(6)