Pieter R. Cullis

University of British Columbia — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

108h-index53.8kcitations411works17.42yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Lipid Membrane Structure and Behavior(191), RNA Interference and Gene Delivery(180), Advanced biosensing and bioanalysis techniques(100), Nanoparticle-Based Drug Delivery(77), Protein Structure and Dynamics(22)

Publications411 total

Age-associated increases in PAI-1 silenced with siRNA-lipid nanoparticles reduces thrombosis and prolongs lifespan
Blood·2026Open Access
Single-Particle Multiparametric Microscopy Reveals Structural, Size, and Payload Heterogeneity in mRNA-Loaded Lipid Nanoparticles
ACS Nano·2025
Lipid nanoparticle mediated base editing of the Q344X rhodopsin mutation associated with retinitis pigmentosa
Gene Therapy·2025
Development of a JAK2V617F-targeting lipid nanoparticle-siRNA as a novel gene therapy for myeloproliferative neoplasms
Blood·2025
Single-particle multi-parametric microscopy reveals structural, size, and payload heterogeneity in mRNA-loaded lipid nanoparticles
2025Open Access
Lipid-based nanoparticles external triggered release strategies in cancer nanomedicine
Journal of Nanobiotechnology·2025· 1 citedOpen Access
A Machine Learning Assisted Tool and Numerical Model for Analyzing Lipid Nanoparticles
ACS Nano·2025· 1 cited
Design of cationic ionizable lipids for the delivery of therapeutic nucleic acids
Molecular Therapy — Methods & Clinical Development·2025· 4 citedOpen Access
Reversing PAI-1 deficiency in blood using mRNA lipid nanoparticles
Molecular Therapy — Methods & Clinical Development·2025Open Access
Multiparametric Characterization of Individual Suspended Nanoparticles Using Confocal Fluorescence and Interferometric Scattering Microscopy with Microfluidic Confinement
Nano Letters·2025· 3 citedOpen Access
Liposomal delivery of a disulfiram metabolite drives copper-mediated tumor immunity
International Journal of Pharmaceutics·2025· 2 citedOpen Access
Multiparametric Characterization of Individual Suspended Nanoparticles using Confocal Fluorescence and Interferometric Scattering Microscopy with Microfluidic Confinement
2025Open Access
Lung tissue-optimized gene editing in human cystic fibrosis models following topical application of lipid nanoparticles
Journal of Controlled Release·2025· 1 cited
Spatially Defined Post-manufacturing Loading of Nanoparticles into Hydrogel-Forming Microneedles
Molecular Pharmaceutics·2025
NANOSPRESSO: toward personalized, locally produced nucleic acid nanomedicines
Frontiers in Science·2025· 11 citedOpen Access
Rational design of lipid nanoparticles for enabling gene therapies
Molecular Therapy — Methods & Clinical Development·2025· 8 citedOpen Access
Liposomal lipid nanoparticles for extrahepatic delivery of mRNA
Nature Communications·2025· 30 citedOpen Access
Advancing Medical Applications of Cancer Nanotechnology: Highlighting Two Decades of the <scp>NCI</scp>'S Nanotechnology Characterization Laboratory Service to the Research Community
Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology·2025· 1 citedOpen Access
From COVID to cancer: Why Canada’s RNA vaccine leadership matters more than ever
2025
RNA lipid nanoparticles stabilized during nebulization through excipient selection
Nanoscale Advances·2025· 3 citedOpen Access
page 1 of 21Next →

Frequent Co-authors

Michael J. Hope(15), Jayesh A. Kulkarni(8), Sam Chen(8), Ying K. Tam(7), Thomas D. Madden(7), Dominik Witzigmann(7), Roy van der Meel(7), Marcel B. Bally(6), Sean C. Semple(6), Ismail M. Hafez(6), Akin Akinc(5), Barbara L. Mui(5), Muthusamy Jayaraman(5), Martin A. Maier(5), Muthiah Manoharan(5), Steven M. Ansell(5), Yuen Yi C. Tam(5), Kallanthottathil G. Rajeev(4), Xinyao Du(4), Paulo J.C. Lin(4)