Paulo J.C. Lin

Acuitas Therapeutics (Canada) — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index6.5kcitations95works6.72yr avg
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Research Topics

RNA Interference and Gene Delivery(31), SARS-CoV-2 and COVID-19 Research(22), Immunotherapy and Immune Responses(20), Advanced biosensing and bioanalysis techniques(13), Virus-based gene therapy research(11)

Publications95 total

Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice
2025Open Access
Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice
2025Open Access
mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines elicits distinct antibody epitope signatures
2025· 1 citedOpen Access
Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice
Science Translational Medicine·2025· 8 cited
Treatment of a metabolic liver disease in mice with a transient prime editing approach
Universität Zürich, ZORA·2025Open Access
Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice
2025· 1 citedOpen Access
Treatment of a metabolic liver disease in mice with a transient prime editing approach
Nature Biomedical Engineering·2025· 12 citedOpen Access
Predicting adenine base editing efficiencies in different cellular contexts by deep learning
Universität Zürich, ZORA·2025Open Access
Predicting adenine base editing efficiencies in different cellular contexts by deep learning
Genome biology·2025· 2 citedOpen Access
Author Correction: Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals
Communications Biology·2025Open Access
Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals
Cell·2024· 33 citedOpen Access
mRNA lipid nanoparticles expressing cell-surface cleavage independent HIV Env trimers elicit autologous tier-2 neutralizing antibodies
Frontiers in Immunology·2024· 11 citedOpen Access
Computationally designed mRNA-launched protein nanoparticle vaccines
2024· 7 citedOpen Access
Exploring Mechanisms of Lipid Nanoparticle‐Mucus Interactions in Healthy and Cystic Fibrosis Conditions
Advanced Healthcare Materials·2024· 27 citedOpen Access
Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth
npj Vaccines·2024· 11 citedOpen Access
Author Correction: A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax
npj Vaccines·2024· 2 citedOpen Access
Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals
2024· 8 citedOpen Access
Immunotherapeutic effects of specific and nonspecific mRNA‐lipid nanoparticles in a mouse model of HDM‐induced airway inflammation
Allergy·2024· 4 citedOpen Access
Treatment of a genetic liver disease in mice through transient prime editor expression
2024· 4 citedOpen Access
Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions
2024· 2 citedOpen Access
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Frequent Co-authors

Ying K. Tam(33), Norbert Pardi(16), Drew Weissman(15), Pieter R. Cullis(15), Hiromi Muramatsu(11), Mohamad‐Gabriel Alameh(9), Sam Chen(8), Yuen Yi C. Tam(7), István Tombácz(4), Barbara L. Mui(4), Katalin Karikó(4), Katlyn Lederer(3), Chutamath Sittplangkoon(3), Brian T. Gaudette(3), Philip Hicks(3), Tomaz B. Manzoni(3), James J. Knox(3), Dorottya Laczkó(3), Shirin Strohmeier(3), Florian Krammer(3)