Aaron R. Thorner

Dana-Farber Cancer Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index12.6kcitations278works4.72yr avg
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Research Topics

Cancer Genomics and Diagnostics(91), Sarcoma Diagnosis and Treatment(49), Lung Cancer Treatments and Mutations(26), Renal cell carcinoma treatment(26), Lymphoma Diagnosis and Treatment(21)

Publications278 total

Single-cell epigenetic profiling reveals a tumor-intrinsic interferon response program in ccRCC tied to poor prognosis and <i>BAP1</i> loss
Science Advances·2026Open Access
Abstract B057: Decoding tumor microenvironment and resistance following immune checkpoint inhibition therapy in anaplastic thyroid carcinoma
Cancer Immunology Research·2026
Feasibility of Post-Transplant Decitabine and G-CSF Maintenance in Children and Young Adults with Myeloid Malignancies: Interim Results from the More Trial
Transplantation and Cellular Therapy·2026
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity
Science Translational Medicine·2026
Evaluation of single-cell RNA profiling technologies using FFPE, fresh, and frozen ccRCC tumor specimens
2025Open Access
Cellular reprogramming during anti-PD-1 and chemotherapy treatment in early-stage primary hormone receptor-positive breast cancer
Nature Communications·2025· 2 citedOpen Access
Understanding tumor-immune-stromal dynamics driving response and resistance to immune checkpoint blockade in melanoma 4125
The Journal of Immunology·2025Open Access
33fusion derived oncogenic programs shape the immune landscape in translocation renal cell carcinoma
The Oncologist·2025Open Access
Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma
2025· 1 citedOpen Access
Abstract 6256: Dissecting tumor-intrinsic programs and immune dynamics driving response to immunotherapy in metastatic melanoma through non-negative matrix factorization decomposition
Cancer Research·2025
Abstract 6605: Spatially-resolved single-cell transcriptome landscape of response and resistance to CDK4/6 inhibitors in patients with hormone receptor-positive metastatic breast cancer
Cancer Research·2025
Abstract 1180: Epigenetic dysregulation of IGF1 and PPARG2 in dedifferentiated liposarcoma
Cancer Research·2025
Abstract 4536: Dissecting tumor-immune microenvironment in response and resistance to immune checkpoint blockade in metastatic melanoma
Cancer Research·2025
Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Nature Medicine·2025Open Access
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity
2025· 1 citedOpen Access
Single-cell epigenetic profiling reveals an interferon response-high program associated with <i>BAP1</i> deficiency in kidney cancer
2024· 4 citedOpen Access
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Nature Medicine·2024· 50 citedOpen Access
P1.01B.02 The Genomic Landscape of Lung Cancer in Never-Smokers from the Women's Health Initiative
Journal of Thoracic Oncology·2024Open Access
The genomic landscape of lung cancer in never-smokers from the Women’s Health Initiative
JCI Insight·2024· 12 citedOpen Access
Abstract 2486: Dissecting tumor-immune interaction in response and resistance to immune checkpoint blockade in metastatic melanoma
Cancer Research·2024
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Frequent Co-authors

Paul Van Hummelen(17), Matthew Meyerson(15), Matthew D. Ducar(13), Anwesha Nag(12), Gad Getz(9), Bruce M. Wollison(9), Rameen Beroukhim(8), Chip Stewart(7), Todd R. Golub(7), Scott J. Rodig(7), Margaret A. Shipp(7), Priscilla K. Brastianos(7), Sandro Santagata(7), William C. Hahn(7), Keith L. Ligon(6), Gavin Ha(6), David J. Kwiatkowski(6), Bjoern Chapuy(5), Andrew Dunford(5), Amaro Taylor‐Weiner(5)